FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976185361> ?p ?o ?g. }

• W1976185361 endingPage "5188" @default.
• W1976185361 startingPage "5184" @default.
• W1976185361 abstract "The novel PEGylated lipoic acid (LA) derivatives with functionality were synthesized in satisfactory yield by simple procedures and evaluated about its anti-melanogenic activity on the B16F10 melanoma cells. Grafting a PEG moiety onto the carboxyl group of LA has reduced the cell cytotoxicity and provided the water solubility and functionality to incorporate the other bioactive moieties. We have found that derivatives showed inhibition of melanin formation by up to 36.5% at 0.1 mM, whereas LA decreased the melanin formation by 8.6%. In addition, it also inhibits at least 86.4% UV-induced MMP-1 expression at 0.1 mM which is higher than LA. These data suggest that the novel PEGylated LA derivatives with functionality may thus serve as a potentially effective anti-melanogenic and anti-aging agent." @default.
• W1976185361 created "2016-06-24" @default.
• W1976185361 creator A5059701191 @default.
• W1976185361 creator A5064167536 @default.
• W1976185361 creator A5073983312 @default.
• W1976185361 date "2011-10-01" @default.
• W1976185361 modified "2023-10-11" @default.
• W1976185361 title "Design, synthesis and evaluation of PEGylated lipoic acid derivatives with functionality as potent anti-melanogenic agents" @default.
• W1976185361 cites W1564875712 @default.
• W1976185361 cites W1965696818 @default.
• W1976185361 cites W1969309377 @default.
• W1976185361 cites W1975322053 @default.
• W1976185361 cites W1984272042 @default.
• W1976185361 cites W1985729602 @default.
• W1976185361 cites W1985970349 @default.
• W1976185361 cites W1994398874 @default.
• W1976185361 cites W1995983044 @default.
• W1976185361 cites W2002392171 @default.
• W1976185361 cites W2010353908 @default.
• W1976185361 cites W2010842231 @default.
• W1976185361 cites W2012168285 @default.
• W1976185361 cites W2017152447 @default.
• W1976185361 cites W2043584813 @default.
• W1976185361 cites W2057948101 @default.
• W1976185361 cites W2071164646 @default.
• W1976185361 cites W2089336861 @default.
• W1976185361 cites W2092676938 @default.
• W1976185361 cites W2093612970 @default.
• W1976185361 cites W2110607710 @default.
• W1976185361 cites W2133095097 @default.
• W1976185361 cites W2136863095 @default.
• W1976185361 cites W2149250648 @default.
• W1976185361 cites W2172982525 @default.
• W1976185361 cites W2325941882 @default.
• W1976185361 cites W2516993077 @default.
• W1976185361 cites W2950479700 @default.
• W1976185361 cites W2952270498 @default.
• W1976185361 doi "https://doi.org/10.1016/j.ejmech.2011.07.056" @default.
• W1976185361 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21890247" @default.
• W1976185361 hasPublicationYear "2011" @default.
• W1976185361 type Work @default.
• W1976185361 sameAs 1976185361 @default.
• W1976185361 citedByCount "12" @default.
• W1976185361 countsByYear W19761853612012 @default.
• W1976185361 countsByYear W19761853612013 @default.
• W1976185361 countsByYear W19761853612014 @default.
• W1976185361 countsByYear W19761853612016 @default.
• W1976185361 countsByYear W19761853612017 @default.
• W1976185361 countsByYear W19761853612019 @default.
• W1976185361 countsByYear W19761853612020 @default.
• W1976185361 countsByYear W19761853612021 @default.
• W1976185361 countsByYear W19761853612022 @default.
• W1976185361 crossrefType "journal-article" @default.
• W1976185361 hasAuthorship W1976185361A5059701191 @default.
• W1976185361 hasAuthorship W1976185361A5064167536 @default.
• W1976185361 hasAuthorship W1976185361A5073983312 @default.
• W1976185361 hasConcept C10138342 @default.
• W1976185361 hasConcept C107538193 @default.
• W1976185361 hasConcept C109316439 @default.
• W1976185361 hasConcept C155574463 @default.
• W1976185361 hasConcept C162324750 @default.
• W1976185361 hasConcept C178790620 @default.
• W1976185361 hasConcept C185592680 @default.
• W1976185361 hasConcept C202751555 @default.
• W1976185361 hasConcept C21951064 @default.
• W1976185361 hasConcept C2776568683 @default.
• W1976185361 hasConcept C2778004101 @default.
• W1976185361 hasConcept C2779491571 @default.
• W1976185361 hasConcept C54400483 @default.
• W1976185361 hasConcept C55493867 @default.
• W1976185361 hasConcept C71240020 @default.
• W1976185361 hasConcept C71924100 @default.
• W1976185361 hasConcept C98274493 @default.
• W1976185361 hasConceptScore W1976185361C10138342 @default.
• W1976185361 hasConceptScore W1976185361C107538193 @default.
• W1976185361 hasConceptScore W1976185361C109316439 @default.
• W1976185361 hasConceptScore W1976185361C155574463 @default.
• W1976185361 hasConceptScore W1976185361C162324750 @default.
• W1976185361 hasConceptScore W1976185361C178790620 @default.
• W1976185361 hasConceptScore W1976185361C185592680 @default.
• W1976185361 hasConceptScore W1976185361C202751555 @default.
• W1976185361 hasConceptScore W1976185361C21951064 @default.
• W1976185361 hasConceptScore W1976185361C2776568683 @default.
• W1976185361 hasConceptScore W1976185361C2778004101 @default.
• W1976185361 hasConceptScore W1976185361C2779491571 @default.
• W1976185361 hasConceptScore W1976185361C54400483 @default.
• W1976185361 hasConceptScore W1976185361C55493867 @default.
• W1976185361 hasConceptScore W1976185361C71240020 @default.
• W1976185361 hasConceptScore W1976185361C71924100 @default.
• W1976185361 hasConceptScore W1976185361C98274493 @default.
• W1976185361 hasIssue "10" @default.
• W1976185361 hasLocation W19761853611 @default.
• W1976185361 hasLocation W19761853612 @default.
• W1976185361 hasOpenAccess W1976185361 @default.
• W1976185361 hasPrimaryLocation W19761853611 @default.
• W1976185361 hasRelatedWork W1480924375 @default.
• W1976185361 hasRelatedWork W1967409193 @default.
• W1976185361 hasRelatedWork W2074857616 @default.

• next