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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976191601> ?p ?o ?g. }

• W1976191601 endingPage "342" @default.
• W1976191601 startingPage "336" @default.
• W1976191601 abstract "It has been suggested that polycythemia vera (PV) could be preceded by an early phase of the disease (e-PV), in which the increase in the red cell parameters is lower than required for a PV diagnosis. In this study, we compared the clinicopathologic and molecular features of 17 patients with e-PV with those of 14 patients with essential thrombocythemia (ET) and 19 with PV. The results for e-PV were more similar to those for PV than for ET. In fact, patients with e-PV were characterized by an increase in the red cell parameters, splenomegaly (P<.05), and hepatomegaly (P=.038), together with hypercellular bone marrow due to increased erythropoiesis and granulopoiesis, associated with megakaryocytic hyperplasia, with pleomorphic aggregates (P<.001). The frequency of the JAK2V617F mutation was similar in e-PV (16 cases tested [100%]) and PV (18/19 [95%]) but was significantly lower (7/13 [54%]) in ET (P=.0007). We propose a diagnostic algorithm helpful to distinguish ET from the early prepolycythemic phase of PV." @default.
• W1976191601 created "2016-06-24" @default.
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• W1976191601 date "2008-09-01" @default.
• W1976191601 modified "2023-09-26" @default.
• W1976191601 title "The Significance of Bone Marrow Biopsy and<i>JAK2</i><i>^V617F</i>Mutation in the Differential Diagnosis Between the “Early” Prepolycythemic Phase of Polycythemia Vera and Essential Thrombocythemia" @default.
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• W1976191601 doi "https://doi.org/10.1309/6bq5k8lhvyakuaf4" @default.
• W1976191601 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18701405" @default.
• W1976191601 hasPublicationYear "2008" @default.
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