FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976200262> ?p ?o ?g. }

• W1976200262 endingPage "469" @default.
• W1976200262 startingPage "459" @default.
• W1976200262 abstract "The aim of this study was to identify the receptor type(s) by which 5-hydroxytryptamine applied to the intestinal mucosa excites the terminals of myenteric AH neurons. The AH neurons have been identified as the intrinsic primary afferent (sensory) neurons in guinea-pig small intestine and 5-hydroxytryptamine has been identified as a possible intermediate in the sensory transduction process. Intracellular recordings were taken from AH neurons located within 1mm of intact mucosa to which 5-hydroxytryptamine was applied. Trains of action potentials and/or slow depolarizing responses were recorded in AH neurons in response to mucosal application of 5-hydroxytryptamine (10 or 20microM) or the 5-hydroxytryptamine-3 receptor agonist, 2-methyl-5-hydroxytryptamine (1 or 3mM), and to electrical stimulation of the mucosa. The 5-hydroxytryptamine-2 receptor agonist, alpha-methyl-5-hydroxytryptamine (100microM), and the 5-hydroxytryptamine-1,2,4 receptor agonist, 5-methoxytryptamine (10microM), did not elicit such responses. The 5-hydroxytryptamine-3 receptor-selective antagonist, granisetron (typically 1microM), and the 5-hydroxytryptamine-3,4 receptor antagonist, tropisetron (typically 1microM), each reduced or abolished the responses to 5-hydroxytryptamine, while the selective 5-hydroxytryptamine-4 receptor antagonist, SB 204070 (1microM), did not. It is concluded that application of 5-hydroxytryptamine to the mucosa activates a 5-hydroxytryptamine-3 receptor that triggers action potential generation in the mucosal nerve terminals of myenteric AH neurons." @default.
• W1976200262 created "2016-06-24" @default.
• W1976200262 creator A5006402971 @default.
• W1976200262 creator A5011971421 @default.
• W1976200262 creator A5020614188 @default.
• W1976200262 creator A5060226120 @default.
• W1976200262 date "2000-11-01" @default.
• W1976200262 modified "2023-10-15" @default.
• W1976200262 title "The terminals of myenteric intrinsic primary afferent neurons of the guinea-pig ileum are excited by 5-hydroxytryptamine acting at 5-hydroxytryptamine-3 receptors" @default.
• W1976200262 cites W1662913097 @default.
• W1976200262 cites W1969087699 @default.
• W1976200262 cites W1969356438 @default.
• W1976200262 cites W1973001367 @default.
• W1976200262 cites W1976200262 @default.
• W1976200262 cites W1991050567 @default.
• W1976200262 cites W1996852467 @default.
• W1976200262 cites W2002297978 @default.
• W1976200262 cites W2002852335 @default.
• W1976200262 cites W2003179935 @default.
• W1976200262 cites W2008257828 @default.
• W1976200262 cites W2009046255 @default.
• W1976200262 cites W2041228343 @default.
• W1976200262 cites W2044183089 @default.
• W1976200262 cites W2044239012 @default.
• W1976200262 cites W2048628319 @default.
• W1976200262 cites W2058278066 @default.
• W1976200262 cites W2058585578 @default.
• W1976200262 cites W2059679962 @default.
• W1976200262 cites W2070682114 @default.
• W1976200262 cites W2072313077 @default.
• W1976200262 cites W2091014133 @default.
• W1976200262 cites W2095980876 @default.
• W1976200262 cites W2098145209 @default.
• W1976200262 cites W2098976206 @default.
• W1976200262 cites W2125055738 @default.
• W1976200262 cites W4231002230 @default.
• W1976200262 doi "https://doi.org/10.1016/s0306-4522(00)00363-8" @default.
• W1976200262 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11074168" @default.
• W1976200262 hasPublicationYear "2000" @default.
• W1976200262 type Work @default.
• W1976200262 sameAs 1976200262 @default.
• W1976200262 citedByCount "184" @default.
• W1976200262 countsByYear W19762002622012 @default.
• W1976200262 countsByYear W19762002622013 @default.
• W1976200262 countsByYear W19762002622014 @default.
• W1976200262 countsByYear W19762002622015 @default.
• W1976200262 countsByYear W19762002622016 @default.
• W1976200262 countsByYear W19762002622017 @default.
• W1976200262 countsByYear W19762002622018 @default.
• W1976200262 countsByYear W19762002622019 @default.
• W1976200262 countsByYear W19762002622020 @default.
• W1976200262 countsByYear W19762002622021 @default.
• W1976200262 countsByYear W19762002622022 @default.
• W1976200262 countsByYear W19762002622023 @default.
• W1976200262 crossrefType "journal-article" @default.
• W1976200262 hasAuthorship W1976200262A5006402971 @default.
• W1976200262 hasAuthorship W1976200262A5011971421 @default.
• W1976200262 hasAuthorship W1976200262A5020614188 @default.
• W1976200262 hasAuthorship W1976200262A5060226120 @default.
• W1976200262 hasConcept C126322002 @default.
• W1976200262 hasConcept C134018914 @default.
• W1976200262 hasConcept C169760540 @default.
• W1976200262 hasConcept C170493617 @default.
• W1976200262 hasConcept C185592680 @default.
• W1976200262 hasConcept C204232928 @default.
• W1976200262 hasConcept C24998067 @default.
• W1976200262 hasConcept C2775864247 @default.
• W1976200262 hasConcept C2776885963 @default.
• W1976200262 hasConcept C2776907353 @default.
• W1976200262 hasConcept C2778122271 @default.
• W1976200262 hasConcept C2778938600 @default.
• W1976200262 hasConcept C53910766 @default.
• W1976200262 hasConcept C71924100 @default.
• W1976200262 hasConcept C86803240 @default.
• W1976200262 hasConceptScore W1976200262C126322002 @default.
• W1976200262 hasConceptScore W1976200262C134018914 @default.
• W1976200262 hasConceptScore W1976200262C169760540 @default.
• W1976200262 hasConceptScore W1976200262C170493617 @default.
• W1976200262 hasConceptScore W1976200262C185592680 @default.
• W1976200262 hasConceptScore W1976200262C204232928 @default.
• W1976200262 hasConceptScore W1976200262C24998067 @default.
• W1976200262 hasConceptScore W1976200262C2775864247 @default.
• W1976200262 hasConceptScore W1976200262C2776885963 @default.
• W1976200262 hasConceptScore W1976200262C2776907353 @default.
• W1976200262 hasConceptScore W1976200262C2778122271 @default.
• W1976200262 hasConceptScore W1976200262C2778938600 @default.
• W1976200262 hasConceptScore W1976200262C53910766 @default.
• W1976200262 hasConceptScore W1976200262C71924100 @default.
• W1976200262 hasConceptScore W1976200262C86803240 @default.
• W1976200262 hasIssue "2" @default.
• W1976200262 hasLocation W19762002621 @default.
• W1976200262 hasLocation W19762002622 @default.
• W1976200262 hasOpenAccess W1976200262 @default.
• W1976200262 hasPrimaryLocation W19762002621 @default.
• W1976200262 hasRelatedWork W1976805986 @default.
• W1976200262 hasRelatedWork W2058091174 @default.
• W1976200262 hasRelatedWork W2156790153 @default.
• W1976200262 hasRelatedWork W2419529664 @default.

• next