Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976202208> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1976202208 endingPage "1131" @default.
- W1976202208 startingPage "1124" @default.
- W1976202208 abstract "Cytogenetic analysis was performed on human papillomavirus (HPV)-immortalized cell lines. Lines were established by co-transfection of primary human keratinocyte cells with HPV type 16 or 18 DNA and pSV2neo. The resulting clonal lines contained integrated HPV DNA and exhibited extended life spans in culture but were non-tumorigenic in nude mice. Two HPV16-immortalized lines (FEPE1L8 and FEPE1L9) and 4 HPV18-immortalized lines (FEA, FEH18L, FEP18-5 and FEP18-11) were established. Two additional lines were derived by subsequent treatment of the FEA line with TPA and by further transfection with HSVII DNA. Cytogenetic analysis revealed that all lines were abnormal, containing a variety of numerical and structural aberrations. Six of the 8 lines were hyper-triploid and 2 were near-diploid. Examination of lines FEA, FEH18L and FEP18-11 at multiple passages in culture revealed that the lines were clonal and chromosomally stable over extended passage in culture. Structural rearrangements were most common in chromosomes 1 and 3 but also occurred in chromosomes 5, 7, 8, 12, 16 and 22. Marker chromosomes were present in all cell lines. A small metacentric marker, possibly an isochromosome for the short arm of chromosome 5, was consistently present in the FEA line and its derivatives (FEAB10 and FEAT) as well as the FEH18L line. A loss or reduction in copy number of chromosome 13 was seen in 5 of the 8 cell lines." @default.
- W1976202208 created "2016-06-24" @default.
- W1976202208 creator A5028556856 @default.
- W1976202208 creator A5044893380 @default.
- W1976202208 creator A5078564000 @default.
- W1976202208 creator A5091170830 @default.
- W1976202208 date "1989-12-15" @default.
- W1976202208 modified "2023-10-18" @default.
- W1976202208 title "Cytogenetic analysis of eight human papillomavirus immortalized human keratinocyte cell lines" @default.
- W1976202208 cites W1562340509 @default.
- W1976202208 cites W1638853330 @default.
- W1976202208 cites W1858263251 @default.
- W1976202208 cites W1859817013 @default.
- W1976202208 cites W1864196634 @default.
- W1976202208 cites W1894672379 @default.
- W1976202208 cites W1967960141 @default.
- W1976202208 cites W1969074708 @default.
- W1976202208 cites W1972753879 @default.
- W1976202208 cites W1975306242 @default.
- W1976202208 cites W1977442544 @default.
- W1976202208 cites W1993769695 @default.
- W1976202208 cites W2018733832 @default.
- W1976202208 cites W2025535009 @default.
- W1976202208 cites W2030216582 @default.
- W1976202208 cites W2040307692 @default.
- W1976202208 cites W2046115366 @default.
- W1976202208 cites W2052788252 @default.
- W1976202208 cites W2072973893 @default.
- W1976202208 cites W2085806332 @default.
- W1976202208 cites W2089215342 @default.
- W1976202208 cites W2090625591 @default.
- W1976202208 cites W2106476914 @default.
- W1976202208 cites W2150311615 @default.
- W1976202208 cites W2334638778 @default.
- W1976202208 cites W714337 @default.
- W1976202208 doi "https://doi.org/10.1002/ijc.2910440631" @default.
- W1976202208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2558081" @default.
- W1976202208 hasPublicationYear "1989" @default.
- W1976202208 type Work @default.
- W1976202208 sameAs 1976202208 @default.
- W1976202208 citedByCount "45" @default.
- W1976202208 countsByYear W19762022082017 @default.
- W1976202208 crossrefType "journal-article" @default.
- W1976202208 hasAuthorship W1976202208A5028556856 @default.
- W1976202208 hasAuthorship W1976202208A5044893380 @default.
- W1976202208 hasAuthorship W1976202208A5078564000 @default.
- W1976202208 hasAuthorship W1976202208A5091170830 @default.
- W1976202208 hasConcept C104317684 @default.
- W1976202208 hasConcept C130773972 @default.
- W1976202208 hasConcept C153911025 @default.
- W1976202208 hasConcept C174475383 @default.
- W1976202208 hasConcept C30481170 @default.
- W1976202208 hasConcept C53226629 @default.
- W1976202208 hasConcept C54009773 @default.
- W1976202208 hasConcept C54355233 @default.
- W1976202208 hasConcept C57269778 @default.
- W1976202208 hasConcept C6045943 @default.
- W1976202208 hasConcept C81885089 @default.
- W1976202208 hasConcept C86803240 @default.
- W1976202208 hasConceptScore W1976202208C104317684 @default.
- W1976202208 hasConceptScore W1976202208C130773972 @default.
- W1976202208 hasConceptScore W1976202208C153911025 @default.
- W1976202208 hasConceptScore W1976202208C174475383 @default.
- W1976202208 hasConceptScore W1976202208C30481170 @default.
- W1976202208 hasConceptScore W1976202208C53226629 @default.
- W1976202208 hasConceptScore W1976202208C54009773 @default.
- W1976202208 hasConceptScore W1976202208C54355233 @default.
- W1976202208 hasConceptScore W1976202208C57269778 @default.
- W1976202208 hasConceptScore W1976202208C6045943 @default.
- W1976202208 hasConceptScore W1976202208C81885089 @default.
- W1976202208 hasConceptScore W1976202208C86803240 @default.
- W1976202208 hasIssue "6" @default.
- W1976202208 hasLocation W19762022081 @default.
- W1976202208 hasLocation W19762022082 @default.
- W1976202208 hasOpenAccess W1976202208 @default.
- W1976202208 hasPrimaryLocation W19762022081 @default.
- W1976202208 hasRelatedWork W1970446973 @default.
- W1976202208 hasRelatedWork W1976202208 @default.
- W1976202208 hasRelatedWork W2054215162 @default.
- W1976202208 hasRelatedWork W2089798460 @default.
- W1976202208 hasRelatedWork W2395845380 @default.
- W1976202208 hasRelatedWork W2406050923 @default.
- W1976202208 hasRelatedWork W2410194142 @default.
- W1976202208 hasRelatedWork W2415382922 @default.
- W1976202208 hasRelatedWork W2418804232 @default.
- W1976202208 hasRelatedWork W2463010161 @default.
- W1976202208 hasVolume "44" @default.
- W1976202208 isParatext "false" @default.
- W1976202208 isRetracted "false" @default.
- W1976202208 magId "1976202208" @default.
- W1976202208 workType "article" @default.