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• W1976219625 abstract "Epidemiologic studies have indicated that human herpesvirus 8 is implicated in the development of Kaposi sarcoma in different geographic areas worldwide.To provide information on the prevalence of human herpesvirus 8 in Brazil and its association with Kaposi sarcoma.An immunofluorescence assay was performed to test 1,044 serum samples from 747 blood donors, 73 patients presenting to casualty departments, and 224 patients attending sexually transmitted disease/AIDS clinics. The sexually transmitted disease group was composed of 88 patients with HIV (40 Kaposi sarcoma positive, 48 Kaposi sarcoma negative) and 136 patients without HIV.Antibodies to human herpesvirus 8-latent nuclear antigens were found in 34 blood donors (4.6%), and in seven casualty patients (9.6%). The highest frequency of human herpesvirus 8 antibodies was found in the sexually transmitted disease group: 32 HIV-positive patients with Kaposi sarcoma (80%) and seven patients without Kaposi sarcoma (14.6%).The presence of human herpesvirus 8 in patients with HIV was strongly associated with Kaposi sarcoma (odds ratio, 23.4; 95% CI, 7.7-71.4), male gender, homosexual or bisexual orientation, and hepatitis B virus infection, but not with the other sexually transmitted diseases that were investigated." @default.
• W1976219625 created "2016-06-24" @default.
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• W1976219625 date "2000-09-01" @default.
• W1976219625 modified "2023-10-01" @default.
• W1976219625 title "Seroprevalence of Human Herpesvirus 8 and Its Association With Kaposi Sarcoma in Brazil" @default.
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• W1976219625 doi "https://doi.org/10.1097/00007435-200009000-00009" @default.
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