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- W1976256891 abstract "The acute effects of Nifedipine on hepatic venous pressure gradient (HVPG) and estimated hepatic blood flow (EHBF) were investigated in six patients with HBsAg-positive cirrhosis and portal hypertension by simultaneous hepatic venous catheterization. The mean arterial pressure significantly decreased by 18% at 1 h after sublingual administration of 10 mg Nifedipine. Significant increases in heart rate (13%) and cardiac output (20%) were also demonstrated in our patients 1 h after administration of Nifedipine. However, there were no significant changes in HVPG and EHBF after Nifedipine. We conclude that in patients with HBsAg-positive cirrhosis who receive Nifedipine, EHBF is maintained despite a substantial change in systemic hemodynamics, and that Nifedipine is not effective in acutely reducing HVPG." @default.
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- W1976256891 date "2008-12-10" @default.
- W1976256891 modified "2023-09-26" @default.
- W1976256891 title "Lack of effects of Nifedipine on hepatic hemodynamics in patients with HBsAg-positive cirrhosis" @default.
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- W1976256891 doi "https://doi.org/10.1111/j.1600-0676.1987.tb00347.x" @default.
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