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• W1976273670 endingPage "306" @default.
• W1976273670 startingPage "299" @default.
• W1976273670 abstract "Messenger RNAs often contain structures in their 5′-untranslated region that serve to regulate or promote expression of their gene product. Recent structural studies have revealed that riboswitches, which bind a variety of small molecule metabolites, including purine bases, S-adenosylmethionine, amino acids and cofactors, can contain sophisticated tertiary architecture that enables their function, akin to tRNA and rRNA. These structures guide the mRNA to adopt one of two mutually exclusive forms, dictating the outcome of transcription or translation. Another highly structured mRNA element, the viral internal ribosomal entry site, is able to manipulate the ribosome and replace the function of initiation factors to promote gene expression." @default.
• W1976273670 created "2016-06-24" @default.
• W1976273670 creator A5004642468 @default.
• W1976273670 date "2006-06-01" @default.
• W1976273670 modified "2023-10-03" @default.
• W1976273670 title "Structures of regulatory elements in mRNAs" @default.
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• W1976273670 doi "https://doi.org/10.1016/j.sbi.2006.05.001" @default.
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