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• W1976306098 abstract "In this study, we synthesized a series of enantiomerically pure (2R,3R)- and (2R,3S)-disubstituted tetrahydropyrans bearing a CH2O spacer group on the side chain at position 2 of the heterocyclic ring. The in vitro antiproliferative activities of the compounds were examined in the human solid tumor cell lines A2780 (ovarian cancer), SW1573 (non-small cell lung cancer), and WiDr (colon cancer). Overall, the results point out the relevance for antiproliferative activity of the distance between the heterocycle and the unsaturated group." @default.
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• W1976306098 date "2007-02-01" @default.
• W1976306098 modified "2023-10-16" @default.
• W1976306098 title "Synthesis and antiproliferative activity of (2R,3R)-disubstituted tetrahydropyrans. Part 2: Effect of side chain homologation" @default.
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• W1976306098 doi "https://doi.org/10.1016/j.bmcl.2006.10.066" @default.
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