Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976331372> ?p ?o ?g. }
- W1976331372 endingPage "859" @default.
- W1976331372 startingPage "854" @default.
- W1976331372 abstract "RalA GTPase associates with a phospholipase D (PLD) that is activated in v-Src- and v-Ras-transformed cells. Two mammalian PLDs were recently cloned: PLD1, which is activated by Arf family GTPases and dependent upon phosphatidylinositol-4,5-bisphosphate (PIP2), and PLD2, which is also dependent upon PIP2, but not stimulated by Arf. Another PLD has been described that is stimulated by oleate. Evidence is provided that the RalA-assiciated PLD is PLD1. First, the PLD precipitated by RalA from murine fibroblasts was stimulated by Arf, dependent upon PIP2, and inhibited by oleate. Second, immobilized RalA precipitated PLD1 from sf9 insect cells overexpressing PLD1. Third, a series of RalA mutants precipitated PLD activity from both PLD1-expressing insect cells and murine fibroblasts with the same efficiency. And finally, immobilized RalA precipitated PLD1 from a purified PLD1 preparation. These data argue that RalA associates directly with the Arf-responsive, PIP2-dependent PLD1." @default.
- W1976331372 created "2016-06-24" @default.
- W1976331372 creator A5021687717 @default.
- W1976331372 creator A5022175836 @default.
- W1976331372 creator A5034833857 @default.
- W1976331372 creator A5060684279 @default.
- W1976331372 creator A5075304957 @default.
- W1976331372 creator A5082711882 @default.
- W1976331372 creator A5087681834 @default.
- W1976331372 creator A5087789028 @default.
- W1976331372 date "1997-06-01" @default.
- W1976331372 modified "2023-09-27" @default.
- W1976331372 title "RalA Interacts Directly with the Arf-Responsive, PIP2-Dependent Phospholipase D1" @default.
- W1976331372 cites W10133016 @default.
- W1976331372 cites W1489297798 @default.
- W1976331372 cites W1567005075 @default.
- W1976331372 cites W1576671418 @default.
- W1976331372 cites W1585517331 @default.
- W1976331372 cites W1588859815 @default.
- W1976331372 cites W1606298617 @default.
- W1976331372 cites W1838271375 @default.
- W1976331372 cites W1931771387 @default.
- W1976331372 cites W1946879166 @default.
- W1976331372 cites W1967385667 @default.
- W1976331372 cites W1972189437 @default.
- W1976331372 cites W1973624256 @default.
- W1976331372 cites W1976695667 @default.
- W1976331372 cites W1979945257 @default.
- W1976331372 cites W1982304503 @default.
- W1976331372 cites W1986131016 @default.
- W1976331372 cites W1989839956 @default.
- W1976331372 cites W2002460033 @default.
- W1976331372 cites W2007375100 @default.
- W1976331372 cites W2012189464 @default.
- W1976331372 cites W2032581399 @default.
- W1976331372 cites W2050621406 @default.
- W1976331372 cites W2056857208 @default.
- W1976331372 cites W2059655527 @default.
- W1976331372 cites W2066696278 @default.
- W1976331372 cites W2067889127 @default.
- W1976331372 cites W2070023258 @default.
- W1976331372 cites W2072066861 @default.
- W1976331372 cites W2085391208 @default.
- W1976331372 cites W2086524338 @default.
- W1976331372 cites W2092869660 @default.
- W1976331372 cites W2094336459 @default.
- W1976331372 cites W2111525938 @default.
- W1976331372 cites W2132342067 @default.
- W1976331372 cites W2132811374 @default.
- W1976331372 cites W2139868649 @default.
- W1976331372 cites W2145120474 @default.
- W1976331372 cites W214799791 @default.
- W1976331372 cites W2249893227 @default.
- W1976331372 cites W2345105535 @default.
- W1976331372 cites W59209658 @default.
- W1976331372 doi "https://doi.org/10.1006/bbrc.1997.6793" @default.
- W1976331372 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9207251" @default.
- W1976331372 hasPublicationYear "1997" @default.
- W1976331372 type Work @default.
- W1976331372 sameAs 1976331372 @default.
- W1976331372 citedByCount "95" @default.
- W1976331372 countsByYear W19763313722012 @default.
- W1976331372 countsByYear W19763313722013 @default.
- W1976331372 countsByYear W19763313722014 @default.
- W1976331372 countsByYear W19763313722017 @default.
- W1976331372 countsByYear W19763313722018 @default.
- W1976331372 countsByYear W19763313722019 @default.
- W1976331372 countsByYear W19763313722020 @default.
- W1976331372 countsByYear W19763313722021 @default.
- W1976331372 countsByYear W19763313722022 @default.
- W1976331372 crossrefType "journal-article" @default.
- W1976331372 hasAuthorship W1976331372A5021687717 @default.
- W1976331372 hasAuthorship W1976331372A5022175836 @default.
- W1976331372 hasAuthorship W1976331372A5034833857 @default.
- W1976331372 hasAuthorship W1976331372A5060684279 @default.
- W1976331372 hasAuthorship W1976331372A5075304957 @default.
- W1976331372 hasAuthorship W1976331372A5082711882 @default.
- W1976331372 hasAuthorship W1976331372A5087681834 @default.
- W1976331372 hasAuthorship W1976331372A5087789028 @default.
- W1976331372 hasBestOaLocation W19763313721 @default.
- W1976331372 hasConcept C11960822 @default.
- W1976331372 hasConcept C126619667 @default.
- W1976331372 hasConcept C153911025 @default.
- W1976331372 hasConcept C180373561 @default.
- W1976331372 hasConcept C185592680 @default.
- W1976331372 hasConcept C207332259 @default.
- W1976331372 hasConcept C2776909261 @default.
- W1976331372 hasConcept C2778918659 @default.
- W1976331372 hasConcept C2780298669 @default.
- W1976331372 hasConcept C2780610907 @default.
- W1976331372 hasConcept C41625074 @default.
- W1976331372 hasConcept C55493867 @default.
- W1976331372 hasConcept C6182249 @default.
- W1976331372 hasConcept C62478195 @default.
- W1976331372 hasConcept C86803240 @default.
- W1976331372 hasConcept C95444343 @default.
- W1976331372 hasConceptScore W1976331372C11960822 @default.
- W1976331372 hasConceptScore W1976331372C126619667 @default.