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• W1976337106 abstract "PURPOSE: To compare the influence of femtosecond lenticule extraction (FLEx) and small incision lenticule extraction (SMILE) on corneal nerve density and the ocular surface for equivalent degrees of correction of myopia. METHODS: Sixty eyes of 30 patients (8 males and 22 females, mean age: 31.0 ± 6.0 years) were included in the study. The patients underwent FLEx in 1 eye and SMILE in the other eye by random assignment. Subbasal nerve density was measured using confocal microscopy preoperatively and at 1 week, 1 and 3 months, and 1 year postoperatively. Ocular surface parameters such as Schirmer’s test results, tear film break-up time, and corneal sensation were performed preoperatively and at 1 and 3 months postoperatively. RESULTS: In the FLEx group, subbasal nerve density was 18,390 ± 6,090 µ m/mm 2 preoperatively and 5,770 ± 3,490 µ m/mm 2 at 1 year postoperatively ( P < .001, Dunnett’s test). In the SMILE group, subbasal nerve density was 16,810 ± 6,220 µ m/mm 2 preoperatively and 11,870 ± 8,200 µ m/mm 2 at 1 year postoperatively ( P = .21). The decrease in corneal nerve density was significantly less after SMILE than after FLEx at all postoperative visits (Mann–Whitney U test, P < .05). FLEx resulted in a significant decrease in Schirmer’s test results, tear film break-up time, and corneal sensation at all postoperative visits, whereas SMILE induced no significant changes in these parameters ( P > .05). CONCLUSIONS: There was less damage to the sub-basal nerve plexus of the cornea and less effect on the ocular surface parameters after SMILE than after FLEx. [ J Refract Surg . 2015;31(1):10–15.]" @default.
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• W1976337106 title "Influence of Femtosecond Lenticule Extraction and Small Incision Lenticule Extraction on Corneal Nerve Density and Ocular Surface: A 1-Year Prospective, Confocal, Microscopic Study" @default.
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• W1976337106 doi "https://doi.org/10.3928/1081597x-20141218-01" @default.
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