FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976339906> ?p ?o ?g. }

• W1976339906 endingPage "1771" @default.
• W1976339906 startingPage "1755" @default.
• W1976339906 abstract "In 1702, Van Leeuwenhoek was the first to describe the phenomenon of anhydrobiosis in a species of bdelloid rotifer, Philodina roseola. It is the purpose of this review to examine what has been learned since then about the extreme desiccation tolerance in rotifers and how this compares with our understanding of anhydrobiosis in other organisms. Remarkably, much of what is known today about the requirements for successful anhydrobiosis, and the degree of biostability conferred by the dry state, was already determined in principle by the time of Spallanzani in the late 18th century. Most modern research on anhydrobiosis has emphasized the importance of the non-reducing disaccharides trehalose and sucrose, one or other sugar being present at high concentrations during desiccation of anhydrobiotic nematodes, brine shrimp cysts, bakers' yeast, resurrection plants and plant seeds. These sugars are proposed to act as water replacement molecules, and as thermodynamic and kinetic stabilizers of biomolecules and membranes. In apparent contradiction of the prevailing models, recent experiments from our laboratory show that bdelloid rotifers undergo anhydrobiosis without producing trehalose or any analogous molecule. This has prompted us to critically re-examine the association of disaccharides with anhydrobiosis in the literature. Surprisingly, current hypotheses are based almost entirely on in vitro data: there is very limited information which is more than simply correlative in the literature on living systems. In many species, disaccharide accumulation occurs at approximately the same time as desiccation tolerance is acquired. However, several studies indicate that these sugars are not sufficient for anhydrobiosis; furthermore, there is no conclusive evidence, through mutagenesis or functional knockout experiments, for example, that sugars are necessary for anhydrobiosis. Indeed, some plant seeds and micro-organisms, like the rotifer, exhibit excellent desiccation tolerance in the absence of high intracellular sugar concentrations. Accordingly, it seems appropriate to call for a re-evaluation of our understanding of anhydrobiosis and to embark on new experimental programmes to determine the key molecular mechanisms involved." @default.
• W1976339906 created "2016-06-24" @default.
• W1976339906 creator A5000223458 @default.
• W1976339906 creator A5052977323 @default.
• W1976339906 date "2003-04-04" @default.
• W1976339906 modified "2023-10-04" @default.
• W1976339906 title "Resurrecting Van Leeuwenhoek's rotifers: a reappraisal of the role of disaccharides in anhydrobiosis" @default.
• W1976339906 cites W1481540054 @default.
• W1976339906 cites W1544767178 @default.
• W1976339906 cites W1555315430 @default.
• W1976339906 cites W1658672685 @default.
• W1976339906 cites W1899683827 @default.
• W1976339906 cites W1914117083 @default.
• W1976339906 cites W1931878801 @default.
• W1976339906 cites W1965396828 @default.
• W1976339906 cites W1966057102 @default.
• W1976339906 cites W1966535034 @default.
• W1976339906 cites W1966836394 @default.
• W1976339906 cites W1966889185 @default.
• W1976339906 cites W1968840114 @default.
• W1976339906 cites W1968918655 @default.
• W1976339906 cites W1971268268 @default.
• W1976339906 cites W1972148874 @default.
• W1976339906 cites W1974414899 @default.
• W1976339906 cites W1975796113 @default.
• W1976339906 cites W1976654218 @default.
• W1976339906 cites W1978487812 @default.
• W1976339906 cites W1978926148 @default.
• W1976339906 cites W1980191630 @default.
• W1976339906 cites W1980428855 @default.
• W1976339906 cites W1981555241 @default.
• W1976339906 cites W1982183910 @default.
• W1976339906 cites W1983233459 @default.
• W1976339906 cites W1985706410 @default.
• W1976339906 cites W1986115510 @default.
• W1976339906 cites W1987122201 @default.
• W1976339906 cites W1987777454 @default.
• W1976339906 cites W1987984651 @default.
• W1976339906 cites W1989128712 @default.
• W1976339906 cites W1991234026 @default.
• W1976339906 cites W1992929484 @default.
• W1976339906 cites W1993032194 @default.
• W1976339906 cites W1993053406 @default.
• W1976339906 cites W1993140443 @default.
• W1976339906 cites W1994744606 @default.
• W1976339906 cites W1997551399 @default.
• W1976339906 cites W1999167722 @default.
• W1976339906 cites W2000223285 @default.
• W1976339906 cites W2000734002 @default.
• W1976339906 cites W2016264999 @default.
• W1976339906 cites W2016572584 @default.
• W1976339906 cites W2016934035 @default.
• W1976339906 cites W2017143474 @default.
• W1976339906 cites W2023933641 @default.
• W1976339906 cites W2028097346 @default.
• W1976339906 cites W2034911276 @default.
• W1976339906 cites W2035252235 @default.
• W1976339906 cites W2036026814 @default.
• W1976339906 cites W2039607358 @default.
• W1976339906 cites W2041324277 @default.
• W1976339906 cites W2041868620 @default.
• W1976339906 cites W2044554559 @default.
• W1976339906 cites W2045667921 @default.
• W1976339906 cites W2045972444 @default.
• W1976339906 cites W2046435046 @default.
• W1976339906 cites W2046615922 @default.
• W1976339906 cites W2049820913 @default.
• W1976339906 cites W2053981702 @default.
• W1976339906 cites W2056580125 @default.
• W1976339906 cites W2060823909 @default.
• W1976339906 cites W2062534929 @default.
• W1976339906 cites W2064613633 @default.
• W1976339906 cites W2064669043 @default.
• W1976339906 cites W2065930902 @default.
• W1976339906 cites W2066535636 @default.
• W1976339906 cites W2066693993 @default.
• W1976339906 cites W2067735486 @default.
• W1976339906 cites W2072419361 @default.
• W1976339906 cites W2079734908 @default.
• W1976339906 cites W2080538147 @default.
• W1976339906 cites W2082580474 @default.
• W1976339906 cites W2084491800 @default.
• W1976339906 cites W2084755369 @default.
• W1976339906 cites W2086727854 @default.
• W1976339906 cites W2089549787 @default.
• W1976339906 cites W2090324283 @default.
• W1976339906 cites W2090628815 @default.
• W1976339906 cites W2092584544 @default.
• W1976339906 cites W2094221699 @default.
• W1976339906 cites W2095030975 @default.
• W1976339906 cites W2095835283 @default.
• W1976339906 cites W2098772291 @default.
• W1976339906 cites W2101196698 @default.
• W1976339906 cites W2103382953 @default.
• W1976339906 cites W2108605550 @default.
• W1976339906 cites W2113151858 @default.
• W1976339906 cites W2113558834 @default.
• W1976339906 cites W2117335009 @default.

• next