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• W1976341194 abstract "Environmental MutagenesisVolume 12, Issue 2 p. 265-268 Research Article High concentrations of sodium chloride induce a “positive” response at the tk locus of l5178y/tk± mouse lymphoma cells Martha M. Moore, Corresponding Author Martha M. Moore Genetic Toxicology Division, Health Effects Research Laboratory, U.S. Environmental Protection Agency, Environmental Health Research and Testing, Inc., Research Triangle Park, North CarolinaGenetic Toxicology Division, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711Search for more papers by this authorKaren H. Brock, Karen H. Brock Genetic Toxicology Division, Health Effects Research Laboratory, U.S. Environmental Protection Agency, Environmental Health Research and Testing, Inc., Research Triangle Park, North CarolinaSearch for more papers by this author Martha M. Moore, Corresponding Author Martha M. Moore Genetic Toxicology Division, Health Effects Research Laboratory, U.S. Environmental Protection Agency, Environmental Health Research and Testing, Inc., Research Triangle Park, North CarolinaGenetic Toxicology Division, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711Search for more papers by this authorKaren H. Brock, Karen H. Brock Genetic Toxicology Division, Health Effects Research Laboratory, U.S. Environmental Protection Agency, Environmental Health Research and Testing, Inc., Research Triangle Park, North CarolinaSearch for more papers by this author First published: 1988 https://doi.org/10.1002/em.2860120213Citations: 11AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References Ashby J, Ishidate M Jr (1986): Clastogenicity in vitro of the Na, K, Ca and Mg salts of saccharin and of magnesium chloride. Consideration of significance. Mutat Res 163: 63–73. Brusick DJ (1986): Genotoxic effects in cultured mammalian cells produced by low pH treatment conditions and increased ion concentrations. Environ Mutagen 8: 879–886. Brusick DJ (ed) (1987): Genotoxicity produced in cultured mammalian cell assays by treatment conditions. Special Issue of Mutat Res, vol 189 (1). Clive D, Johnson KO, Spector JFS, Batson Ag, Brown MMM (1979): Validation and characterization of the L5178Y/TK+/− mouse lymphoma mutagen assay system. Mutat Res 59: 61–108. Clive D, Spector JFS (1975): Laboratory procedure for assessing specific locus mutations at the TK locus in cultured L5178Y mouse lymphoma cells. Mutat Res 31: 17–29. Galloway SM, Deasy DA, Bean CL, Kraynak AR, Armstrong MJ, Bradley MO (1987): Effects of high osmotic strength on chromosome aberrations, sister-chromatid exchanges and DNA strand breaks, and the relation to toxicity. Mutat Res 189: 15–25. Jotz MM, Mitchell AD (1981): Effects of 20 coded chemicals on the forward mutation frequency at the thymidine kinase locus in L5178Y mouse lymphoma cells. In FJ de Series, J Ashby (eds): “ Evaluation of Short-Term Tests for Carcinogens.” New York: Elsevier, pp 580–593. Meyer M, Brock K, Lawrence K, Casto B, Moore MM (1986): Evaluation of the effect of agar on the results obtained in the L5178Y mouse lymphoma assay. Environ Mutagen 8: 727–740. Moore MM, Clive D (1982): The quantitation of TK−/− and HGPRT− mutants of L5178Y/TK+/− mouse lymphoma cells at varying times post treatment. Environ Mutagen 4: 499–519. Moore MM, Clive D, Howard BE, Batson AG, Turner NT (1985): In situ analysis of trifluorothymidine-resistant (TFT) mutants of L5178Y/TK+/− mouse lymphoma cells. Mutat Res 151: 147–159. Moore MM, Howard BE (1982): Quantitation of small colony trifluorothymidine-resistant mutants of L5178Y/TK+/− mouse lymphoma cells in RPMI-1640 medium. Mutat Res 104: 287–294. Oberly TJ Bewsey BJ, Probst GS (1984): An evaluation of the L5178YTK+/− mouse lymphoma forward assay using 42 chemicals. Mutat Res 125: 291–306. Turner NT, Batson AG, Clive D (1984): Procedures for the L5178Y/TK+/− ≫ TK−/− mouse lymphoma cell mutagenicity assy. In BJ Kilbey, M Legator, W Nichols, C Ramel (eds): “Handbook of Mutagenicity Test Procedures.” Amsterdam. Elsevier, pp 239–268. Citing Literature Volume12, Issue21988Pages 265-268 ReferencesRelatedInformation" @default.
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