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- W1976370246 abstract "Peanut allergy is IgE-mediated type-I hypersensitivity, and T helper 2 cytokines are central to those pathogenesis. We investigated the effects of the administration of chitin and chitosan on peanut-induced hypersensitivities in mouse food allergy models. Chitin and chitosan protected mice against peanut-induced anaphylaxis reactions, and the peanut-specific IgE production decreased by up to 47% with the administration of β-chitosan. The levels of IL-5, IL-13, and IL-10 were significantly suppressed in all groups (α-chitin≥β-chitin≥β-chitosan). These results suggested that the administration of chitin and chitosan from by-products of food processing are beneficial for the prevention of food allergies." @default.
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- W1976370246 date "2013-10-01" @default.
- W1976370246 modified "2023-09-27" @default.
- W1976370246 title "Oral administration of chitin and chitosan prevents peanut-induced anaphylaxis in a murine food allergy model" @default.
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- W1976370246 doi "https://doi.org/10.1016/j.ijbiomac.2013.06.017" @default.
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