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- W1976384369 abstract "A kinetic enzymological assay for methotrexate in serum is described; the results are available after 1.5 hours. The lower limit of sensivity is 50 nmol/1; the day-to-day variation coefficients compare favourably with other procedures (about 7% in the 200-600 nmol/1 range). The method uses purified dihydrofolic acid reductase from bovine liver. The problem of its instability in the assay is circumvented by several measures, e.g. the use of a reaction rate analyser." @default.
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- W1976384369 date "1979-01-01" @default.
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- W1976384369 title "A Rapid Enzymatic Assay for Methotrexate in Serum" @default.
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- W1976384369 doi "https://doi.org/10.1515/cclm.1979.17.4.235" @default.
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