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- W1976448703 abstract "Abstract The 16,16-difluoro analogues of equilin and equilenin methyl ethers have been synthesized. These and other natural and synthetic estrogens have been tested in vitro as inhibitors of cholesterol biosynthesis. All the compounds tested exhibited marked activity, with 16,16-difluoroequilin methyl ether being the most potent, inhibiting by 36 per cent at a concentration of 1 × 10−4 M. The possible role of inhibition of cholesterol biosynthesis in the mechanism of estrogen-induced hypocholesteremia is discussed." @default.
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- W1976448703 date "1962-08-01" @default.
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- W1976448703 title "Agents affecting lipid metabolism-I. on the inhibition of cholesterol biosynthesis by estrogens" @default.
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- W1976448703 doi "https://doi.org/10.1016/0006-2952(62)90043-6" @default.
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