FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976453201> ?p ?o ?g. }

• W1976453201 endingPage "1595" @default.
• W1976453201 startingPage "1590" @default.
• W1976453201 abstract "Phylogenetic reconstructions of the β-globin gene family in vertebrates have revealed that developmentally regulated systems of hemoglobin synthesis have been reinvented multiple times in independent lineages. For example, the functional differentiation of embryonic and adult β-like globin genes occurred independently in birds and mammals. In both taxa, the embryonic β-globin gene is exclusively expressed in primitive erythroid cells derived from the yolk sac. However, the “ε-globin” gene in birds is not orthologous to the ε-globin gene in mammals, because they are independently derived from lineage-specific duplications of a proto β-globin gene. Here, we report evidence that the early and late expressed β-like globin genes in monotremes and therian mammals (marsupials and placental mammals) are the products of independent duplications of a proto β-globin gene in each of these two lineages. Results of our analysis of genomic sequence data from a large number of vertebrate taxa, including sequence from the recently completed platypus genome, reveal that the ε- and β-globin genes of therian mammals arose via duplication of a proto β-globin gene after the therian/monotreme split. Our analysis of genomic sequence from the platypus also revealed the presence of a duplicate pair of β-like globin genes that originated via duplication of a proto β-globin gene in the monotreme lineage. This discovery provides evidence that, in different lineages of mammals, descendent copies of the same proto β-globin gene may have been independently neofunctionalized to perform physiological tasks associated with oxygen uptake and storage during embryonic development." @default.
• W1976453201 created "2016-06-24" @default.
• W1976453201 creator A5013599203 @default.
• W1976453201 creator A5026872382 @default.
• W1976453201 creator A5053052855 @default.
• W1976453201 date "2008-02-05" @default.
• W1976453201 modified "2023-10-17" @default.
• W1976453201 title "Genomic evidence for independent origins of β-like globin genes in monotremes and therian mammals" @default.
• W1976453201 cites W1633681515 @default.
• W1976453201 cites W1964352846 @default.
• W1976453201 cites W1966364301 @default.
• W1976453201 cites W1969482182 @default.
• W1976453201 cites W1974858651 @default.
• W1976453201 cites W2000958402 @default.
• W1976453201 cites W2006918190 @default.
• W1976453201 cites W2015135504 @default.
• W1976453201 cites W2015976662 @default.
• W1976453201 cites W2022898664 @default.
• W1976453201 cites W2025032015 @default.
• W1976453201 cites W2026502449 @default.
• W1976453201 cites W2042206208 @default.
• W1976453201 cites W2044179661 @default.
• W1976453201 cites W2044645232 @default.
• W1976453201 cites W2049885817 @default.
• W1976453201 cites W2056367131 @default.
• W1976453201 cites W2058804004 @default.
• W1976453201 cites W2072603644 @default.
• W1976453201 cites W2075195274 @default.
• W1976453201 cites W2078071339 @default.
• W1976453201 cites W2080429646 @default.
• W1976453201 cites W2081875871 @default.
• W1976453201 cites W2094596493 @default.
• W1976453201 cites W2125121305 @default.
• W1976453201 cites W2129320622 @default.
• W1976453201 cites W2132926880 @default.
• W1976453201 cites W2136530314 @default.
• W1976453201 cites W2146058063 @default.
• W1976453201 cites W2150270014 @default.
• W1976453201 cites W2150309666 @default.
• W1976453201 cites W2156341767 @default.
• W1976453201 cites W2160813350 @default.
• W1976453201 cites W2165845627 @default.
• W1976453201 cites W2166187656 @default.
• W1976453201 cites W2343869275 @default.
• W1976453201 cites W3006626334 @default.
• W1976453201 cites W38643821 @default.
• W1976453201 doi "https://doi.org/10.1073/pnas.0710531105" @default.
• W1976453201 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2234189" @default.
• W1976453201 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18216242" @default.
• W1976453201 hasPublicationYear "2008" @default.
• W1976453201 type Work @default.
• W1976453201 sameAs 1976453201 @default.
• W1976453201 citedByCount "55" @default.
• W1976453201 countsByYear W19764532012012 @default.
• W1976453201 countsByYear W19764532012013 @default.
• W1976453201 countsByYear W19764532012014 @default.
• W1976453201 countsByYear W19764532012015 @default.
• W1976453201 countsByYear W19764532012016 @default.
• W1976453201 countsByYear W19764532012017 @default.
• W1976453201 countsByYear W19764532012018 @default.
• W1976453201 countsByYear W19764532012019 @default.
• W1976453201 countsByYear W19764532012020 @default.
• W1976453201 countsByYear W19764532012021 @default.
• W1976453201 countsByYear W19764532012022 @default.
• W1976453201 crossrefType "journal-article" @default.
• W1976453201 hasAuthorship W1976453201A5013599203 @default.
• W1976453201 hasAuthorship W1976453201A5026872382 @default.
• W1976453201 hasAuthorship W1976453201A5053052855 @default.
• W1976453201 hasBestOaLocation W19764532012 @default.
• W1976453201 hasConcept C104317684 @default.
• W1976453201 hasConcept C125996951 @default.
• W1976453201 hasConcept C139690037 @default.
• W1976453201 hasConcept C141231307 @default.
• W1976453201 hasConcept C2776817793 @default.
• W1976453201 hasConcept C2777322942 @default.
• W1976453201 hasConcept C2778961482 @default.
• W1976453201 hasConcept C2781202234 @default.
• W1976453201 hasConcept C41806617 @default.
• W1976453201 hasConcept C54355233 @default.
• W1976453201 hasConcept C58642233 @default.
• W1976453201 hasConcept C5911399 @default.
• W1976453201 hasConcept C7602840 @default.
• W1976453201 hasConcept C78458016 @default.
• W1976453201 hasConcept C86803240 @default.
• W1976453201 hasConcept C90856448 @default.
• W1976453201 hasConceptScore W1976453201C104317684 @default.
• W1976453201 hasConceptScore W1976453201C125996951 @default.
• W1976453201 hasConceptScore W1976453201C139690037 @default.
• W1976453201 hasConceptScore W1976453201C141231307 @default.
• W1976453201 hasConceptScore W1976453201C2776817793 @default.
• W1976453201 hasConceptScore W1976453201C2777322942 @default.
• W1976453201 hasConceptScore W1976453201C2778961482 @default.
• W1976453201 hasConceptScore W1976453201C2781202234 @default.
• W1976453201 hasConceptScore W1976453201C41806617 @default.
• W1976453201 hasConceptScore W1976453201C54355233 @default.
• W1976453201 hasConceptScore W1976453201C58642233 @default.
• W1976453201 hasConceptScore W1976453201C5911399 @default.
• W1976453201 hasConceptScore W1976453201C7602840 @default.

• next