Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976455959> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W1976455959 endingPage "541" @default.
- W1976455959 startingPage "534" @default.
- W1976455959 abstract "Invasive group A streptococcal (GAS) disease is a condition of clinical and public health significance. We conducted epidemiological analyses to determine if the presence of gastrointestinal (GI) complaints (diarrhea and/or vomiting) early in the course of invasive GAS disease is associated with either of two severe outcomes: GAS necrotizing fasciitis, or hospital mortality. Subjects were hospitalized for invasive GAS disease throughout the state of Florida, USA, during a 4-year period. Multiple imputation using the Markov chain Monte Carlo method was used to replace missing values with plausible values. Excluding cases with missing data resulted in a sample size of 138 invasive GAS patients (the complete subject analysis) while the imputed datasets contained 257 records. GI symptomatology within 48 h of hospital admission was not associated with hospital mortality in either the complete subject analysis [adjusted odds ratio (aOR) 0.86, 95% confidence interval (CI) 0.31-2.39] or in the imputed datasets. GI symptoms were significantly associated with GAS necrotizing fasciitis in the complete subject analysis (aOR 4.64, 95% CI 1.18-18.23) and in the imputed datasets but only in patients aged <55 years. The common cause of GI symptoms and necrotizing fasciitis may be streptococcal exotoxins. Clinicians who are treating young individuals presumed to be in the early stages of invasive GAS disease should take note of GI symptoms and remain vigilant for the development of a GAS necrotizing soft-tissue infection." @default.
- W1976455959 created "2016-06-24" @default.
- W1976455959 creator A5034060036 @default.
- W1976455959 creator A5049282836 @default.
- W1976455959 creator A5072763366 @default.
- W1976455959 date "2009-10-02" @default.
- W1976455959 modified "2023-10-17" @default.
- W1976455959 title "Gastrointestinal symptomatology as a predictor of severe outcomes of invasive group A streptococcal infections" @default.
- W1976455959 cites W139211453 @default.
- W1976455959 cites W1926186855 @default.
- W1976455959 cites W2000521158 @default.
- W1976455959 cites W2018365137 @default.
- W1976455959 cites W2023328614 @default.
- W1976455959 cites W2030197900 @default.
- W1976455959 cites W2040930422 @default.
- W1976455959 cites W2061339649 @default.
- W1976455959 cites W2106008126 @default.
- W1976455959 cites W2135666941 @default.
- W1976455959 cites W2147451560 @default.
- W1976455959 cites W2170674956 @default.
- W1976455959 cites W2171780167 @default.
- W1976455959 cites W2480680997 @default.
- W1976455959 doi "https://doi.org/10.1017/s0950268809990938" @default.
- W1976455959 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19796450" @default.
- W1976455959 hasPublicationYear "2009" @default.
- W1976455959 type Work @default.
- W1976455959 sameAs 1976455959 @default.
- W1976455959 citedByCount "2" @default.
- W1976455959 countsByYear W19764559592012 @default.
- W1976455959 countsByYear W19764559592023 @default.
- W1976455959 crossrefType "journal-article" @default.
- W1976455959 hasAuthorship W1976455959A5034060036 @default.
- W1976455959 hasAuthorship W1976455959A5049282836 @default.
- W1976455959 hasAuthorship W1976455959A5072763366 @default.
- W1976455959 hasBestOaLocation W19764559591 @default.
- W1976455959 hasConcept C107130276 @default.
- W1976455959 hasConcept C126322002 @default.
- W1976455959 hasConcept C141071460 @default.
- W1976455959 hasConcept C156957248 @default.
- W1976455959 hasConcept C187212893 @default.
- W1976455959 hasConcept C203014093 @default.
- W1976455959 hasConcept C2522874641 @default.
- W1976455959 hasConcept C2777217379 @default.
- W1976455959 hasConcept C2778750513 @default.
- W1976455959 hasConcept C2779134260 @default.
- W1976455959 hasConcept C2779802037 @default.
- W1976455959 hasConcept C44249647 @default.
- W1976455959 hasConcept C71924100 @default.
- W1976455959 hasConceptScore W1976455959C107130276 @default.
- W1976455959 hasConceptScore W1976455959C126322002 @default.
- W1976455959 hasConceptScore W1976455959C141071460 @default.
- W1976455959 hasConceptScore W1976455959C156957248 @default.
- W1976455959 hasConceptScore W1976455959C187212893 @default.
- W1976455959 hasConceptScore W1976455959C203014093 @default.
- W1976455959 hasConceptScore W1976455959C2522874641 @default.
- W1976455959 hasConceptScore W1976455959C2777217379 @default.
- W1976455959 hasConceptScore W1976455959C2778750513 @default.
- W1976455959 hasConceptScore W1976455959C2779134260 @default.
- W1976455959 hasConceptScore W1976455959C2779802037 @default.
- W1976455959 hasConceptScore W1976455959C44249647 @default.
- W1976455959 hasConceptScore W1976455959C71924100 @default.
- W1976455959 hasIssue "4" @default.
- W1976455959 hasLocation W19764559591 @default.
- W1976455959 hasLocation W19764559592 @default.
- W1976455959 hasOpenAccess W1976455959 @default.
- W1976455959 hasPrimaryLocation W19764559591 @default.
- W1976455959 hasRelatedWork W1873709087 @default.
- W1976455959 hasRelatedWork W2158937766 @default.
- W1976455959 hasRelatedWork W2347463849 @default.
- W1976455959 hasRelatedWork W2353498255 @default.
- W1976455959 hasRelatedWork W2380870509 @default.
- W1976455959 hasRelatedWork W2419672583 @default.
- W1976455959 hasRelatedWork W2436036196 @default.
- W1976455959 hasRelatedWork W4220674773 @default.
- W1976455959 hasRelatedWork W4309135055 @default.
- W1976455959 hasRelatedWork W4386134360 @default.
- W1976455959 hasVolume "138" @default.
- W1976455959 isParatext "false" @default.
- W1976455959 isRetracted "false" @default.
- W1976455959 magId "1976455959" @default.
- W1976455959 workType "article" @default.