FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976460726> ?p ?o ?g. }

• W1976460726 endingPage "564" @default.
• W1976460726 startingPage "559" @default.
• W1976460726 abstract "Pharmacological evidence suggests that angiotensin II type 1 (AT(1)) receptors are involved in the regulation of cardiovascular response to emotional stress and reinforcing effect of dietary salt on this response. In this study, we examined the effect of genetic deletion of AT(1A) receptors on the cardiovascular effects of stress and salt in mice. AT(1A) receptor knockout (AT(1A)(-/-)) and wild-type (AT(1A)(+/+)) mice were implanted with telemetry devices and placed on a normal (0.4%) or high (3.1%) salt diet (HSD). Resting blood pressure (BP) in AT(1A)(-/-) mice (84+/-3 mm Hg) was lower than in AT(1A)(+/+) mice (107+/-2 mm Hg). Negative emotional (restraint) stress increased BP by 33+/-3 mm Hg in AT(1A)(+/+) mice. This response was attenuated by 40% in AT(1A)(-/-) mice (18+/-3 mm Hg). Conversely, the BP increase caused by food presentation and feeding was similar in AT(1A)(-/-) (25+/-3 mm Hg) and AT(1A)(+/+) mice (26+/-3 mm Hg). HSD increased resting BP by 14+/-4 mm Hg in AT(1A)(-/-) mice without affecting it significantly in AT(1A)(+/+) mice. Under these conditions, the pressor response to restraint stress in AT(1A)(-/-) mice (30+/-3 mm Hg) was no longer different from that in wild-type animals (28+/-3 mm Hg). The BP response to feeding was not altered by HSD in either AT(1A)(-/-) or AT(1A)(+/+) mice (25+/-2 and 27+/-3 mm Hg, respectively). These results indicate that AT(1A) receptor deficiency leads to a reduction in BP reactivity to negative emotional stress, but not feeding. HSD can selectively reinforce the cardiovascular response to negative stress in AT(1A)(-/-) mice. However, there is little interaction between AT(1A) receptors, excess dietary sodium and feeding-induced cardiovascular arousal." @default.
• W1976460726 created "2016-06-24" @default.
• W1976460726 creator A5009553066 @default.
• W1976460726 creator A5025133583 @default.
• W1976460726 creator A5044082368 @default.
• W1976460726 creator A5064692662 @default.
• W1976460726 creator A5075665144 @default.
• W1976460726 date "2009-05-01" @default.
• W1976460726 modified "2023-10-09" @default.
• W1976460726 title "Blood pressure reactivity to emotional stress is reduced in AT1A-receptor knockout mice on normal, but not high salt intake" @default.
• W1976460726 cites W1844072728 @default.
• W1976460726 cites W1973264517 @default.
• W1976460726 cites W1976862576 @default.
• W1976460726 cites W1984735933 @default.
• W1976460726 cites W2005992028 @default.
• W1976460726 cites W2008006493 @default.
• W1976460726 cites W2009926717 @default.
• W1976460726 cites W2026497918 @default.
• W1976460726 cites W2028664377 @default.
• W1976460726 cites W2040525509 @default.
• W1976460726 cites W2055560327 @default.
• W1976460726 cites W2057747760 @default.
• W1976460726 cites W2076978773 @default.
• W1976460726 cites W2085175888 @default.
• W1976460726 cites W2092398829 @default.
• W1976460726 cites W2112285252 @default.
• W1976460726 cites W2116989971 @default.
• W1976460726 cites W2117431648 @default.
• W1976460726 cites W2128741160 @default.
• W1976460726 cites W2132465696 @default.
• W1976460726 cites W2134176302 @default.
• W1976460726 cites W2150417502 @default.
• W1976460726 cites W2152207168 @default.
• W1976460726 cites W2153115306 @default.
• W1976460726 cites W2162341082 @default.
• W1976460726 cites W2165895254 @default.
• W1976460726 cites W2166161383 @default.
• W1976460726 cites W2168699761 @default.
• W1976460726 cites W2336200545 @default.
• W1976460726 doi "https://doi.org/10.1038/hr.2009.59" @default.
• W1976460726 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19407821" @default.
• W1976460726 hasPublicationYear "2009" @default.
• W1976460726 type Work @default.
• W1976460726 sameAs 1976460726 @default.
• W1976460726 citedByCount "27" @default.
• W1976460726 countsByYear W19764607262012 @default.
• W1976460726 countsByYear W19764607262013 @default.
• W1976460726 countsByYear W19764607262015 @default.
• W1976460726 countsByYear W19764607262016 @default.
• W1976460726 countsByYear W19764607262017 @default.
• W1976460726 countsByYear W19764607262018 @default.
• W1976460726 countsByYear W19764607262019 @default.
• W1976460726 countsByYear W19764607262020 @default.
• W1976460726 countsByYear W19764607262021 @default.
• W1976460726 countsByYear W19764607262022 @default.
• W1976460726 countsByYear W19764607262023 @default.
• W1976460726 crossrefType "journal-article" @default.
• W1976460726 hasAuthorship W1976460726A5009553066 @default.
• W1976460726 hasAuthorship W1976460726A5025133583 @default.
• W1976460726 hasAuthorship W1976460726A5044082368 @default.
• W1976460726 hasAuthorship W1976460726A5064692662 @default.
• W1976460726 hasAuthorship W1976460726A5075665144 @default.
• W1976460726 hasBestOaLocation W19764607261 @default.
• W1976460726 hasConcept C126322002 @default.
• W1976460726 hasConcept C134018914 @default.
• W1976460726 hasConcept C170493617 @default.
• W1976460726 hasConcept C182704531 @default.
• W1976460726 hasConcept C185592680 @default.
• W1976460726 hasConcept C2908929049 @default.
• W1976460726 hasConcept C71924100 @default.
• W1976460726 hasConcept C84393581 @default.
• W1976460726 hasConceptScore W1976460726C126322002 @default.
• W1976460726 hasConceptScore W1976460726C134018914 @default.
• W1976460726 hasConceptScore W1976460726C170493617 @default.
• W1976460726 hasConceptScore W1976460726C182704531 @default.
• W1976460726 hasConceptScore W1976460726C185592680 @default.
• W1976460726 hasConceptScore W1976460726C2908929049 @default.
• W1976460726 hasConceptScore W1976460726C71924100 @default.
• W1976460726 hasConceptScore W1976460726C84393581 @default.
• W1976460726 hasIssue "7" @default.
• W1976460726 hasLocation W19764607261 @default.
• W1976460726 hasLocation W19764607262 @default.
• W1976460726 hasOpenAccess W1976460726 @default.
• W1976460726 hasPrimaryLocation W19764607261 @default.
• W1976460726 hasRelatedWork W1992220075 @default.
• W1976460726 hasRelatedWork W2020571025 @default.
• W1976460726 hasRelatedWork W2024736606 @default.
• W1976460726 hasRelatedWork W2033472167 @default.
• W1976460726 hasRelatedWork W2034583712 @default.
• W1976460726 hasRelatedWork W2063619316 @default.
• W1976460726 hasRelatedWork W2091193686 @default.
• W1976460726 hasRelatedWork W2151139437 @default.
• W1976460726 hasRelatedWork W2169225653 @default.
• W1976460726 hasRelatedWork W2312865257 @default.
• W1976460726 hasVolume "32" @default.
• W1976460726 isParatext "false" @default.
• W1976460726 isRetracted "false" @default.
• W1976460726 magId "1976460726" @default.

• next