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• W1976463707 abstract "PurposeTo assess the value of two elastographic methods, ARFI (Acoustic Radiation Force Impulse) and TE (Transient Elastography), for the noninvasive evaluation of liver fibrosis.Material & MethodsWe have studied 96 patients with chronic hepatitis (41 HBV and 55 HCV), mean age 46.9±12.9 years. In each patient, we performed in the same session liver biopsy (evaluated according to the Metavir score), liver stiffness measurements by means of TE and ARFI. 10 LS measurements were performed both by TE and ARFI; median values were calculated and expressed in kPa and m/s, respectively. Only TE and ARFI measurements with IQR<30% and SR≥60% were considered reliable.ResultsThe distribution of liver fibrosis in the study group was: F0-1 patient (1.04%), F1-10 (10.4%), F2-39 (40.6%), F3-28 (29.1%) and F4-18 (18.7%). TE was indeterminable or invalid (IQR≥60% and/or SR<60%) in 16 patients (16.6%). ARFI was determinable in all the cases, but invalid in 12 cases (12.5%). In the whole group, the correlation with fibrosis was similar for TE and ARFI (r = 0.503, p < 0.0001 and r = 0.540, p < 0.0001) (p = 0.74). For significant fibrosis (F≥2, Metavir), the correlation with fibrosis was also similar for the 2 methods (TE: r = 0.502, p < 0.0001 and ARFI: r = 0.551, p < 0.0001) (p = 0.69). The same situation was obtained in the case of severe fibrosis (F≥3, Metavir): for TE, r = 0.604, p = 0.0001 and for ARFI, r = 0.535, p = 0.0005 (p = 0.67).ConclusionThe performance of the two elastographic methods was similar for the assessment of liver fibrosis. PurposeTo assess the value of two elastographic methods, ARFI (Acoustic Radiation Force Impulse) and TE (Transient Elastography), for the noninvasive evaluation of liver fibrosis. To assess the value of two elastographic methods, ARFI (Acoustic Radiation Force Impulse) and TE (Transient Elastography), for the noninvasive evaluation of liver fibrosis. Material & MethodsWe have studied 96 patients with chronic hepatitis (41 HBV and 55 HCV), mean age 46.9±12.9 years. In each patient, we performed in the same session liver biopsy (evaluated according to the Metavir score), liver stiffness measurements by means of TE and ARFI. 10 LS measurements were performed both by TE and ARFI; median values were calculated and expressed in kPa and m/s, respectively. Only TE and ARFI measurements with IQR<30% and SR≥60% were considered reliable. We have studied 96 patients with chronic hepatitis (41 HBV and 55 HCV), mean age 46.9±12.9 years. In each patient, we performed in the same session liver biopsy (evaluated according to the Metavir score), liver stiffness measurements by means of TE and ARFI. 10 LS measurements were performed both by TE and ARFI; median values were calculated and expressed in kPa and m/s, respectively. Only TE and ARFI measurements with IQR<30% and SR≥60% were considered reliable. ResultsThe distribution of liver fibrosis in the study group was: F0-1 patient (1.04%), F1-10 (10.4%), F2-39 (40.6%), F3-28 (29.1%) and F4-18 (18.7%). TE was indeterminable or invalid (IQR≥60% and/or SR<60%) in 16 patients (16.6%). ARFI was determinable in all the cases, but invalid in 12 cases (12.5%). In the whole group, the correlation with fibrosis was similar for TE and ARFI (r = 0.503, p < 0.0001 and r = 0.540, p < 0.0001) (p = 0.74). For significant fibrosis (F≥2, Metavir), the correlation with fibrosis was also similar for the 2 methods (TE: r = 0.502, p < 0.0001 and ARFI: r = 0.551, p < 0.0001) (p = 0.69). The same situation was obtained in the case of severe fibrosis (F≥3, Metavir): for TE, r = 0.604, p = 0.0001 and for ARFI, r = 0.535, p = 0.0005 (p = 0.67). The distribution of liver fibrosis in the study group was: F0-1 patient (1.04%), F1-10 (10.4%), F2-39 (40.6%), F3-28 (29.1%) and F4-18 (18.7%). TE was indeterminable or invalid (IQR≥60% and/or SR<60%) in 16 patients (16.6%). ARFI was determinable in all the cases, but invalid in 12 cases (12.5%). In the whole group, the correlation with fibrosis was similar for TE and ARFI (r = 0.503, p < 0.0001 and r = 0.540, p < 0.0001) (p = 0.74). For significant fibrosis (F≥2, Metavir), the correlation with fibrosis was also similar for the 2 methods (TE: r = 0.502, p < 0.0001 and ARFI: r = 0.551, p < 0.0001) (p = 0.69). The same situation was obtained in the case of severe fibrosis (F≥3, Metavir): for TE, r = 0.604, p = 0.0001 and for ARFI, r = 0.535, p = 0.0005 (p = 0.67). ConclusionThe performance of the two elastographic methods was similar for the assessment of liver fibrosis. The performance of the two elastographic methods was similar for the assessment of liver fibrosis." @default.
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• W1976463707 date "2011-08-01" @default.
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• W1976463707 title "Which Elastographic Method (Transient Elastography or Acoustic Radiation Force Impulse Elastography) Is Better for the Assessment of Liver Fibrosis in Chronic Viral Hepatitis?" @default.
• W1976463707 doi "https://doi.org/10.1016/j.ultrasmedbio.2011.05.726" @default.
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