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• W1976581014 abstract "Staphylococcus aureus is a common etiological factor in infections of burns and other chronic wounds. The development of an effective and fast-acting treatment would be enormously beneficial and is highly desired. We focused on testing the bactericidal efficacy of photoinactivation using a known photosensitizer (protoporphyrin IX, PPIX) in sequential combination with silver nanoparticles against S. aureus. Using PPIX-based photoinactivation followed by silver nanoparticles we obtained a high bactericidal effect (7 log10 units reduction) with limited harmful effects on human epidermal keratinocytes. Moreover, we observed that the use of silver nanoparticles prevents bacterial re-growth 24 h post-PDI treatment. A sequential combination of photoinactivation and silver nanoparticles represents a potentially effective antibacterial approach." @default.
• W1976581014 created "2016-06-24" @default.
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• W1976581014 date "2013-09-01" @default.
• W1976581014 modified "2023-09-27" @default.
• W1976581014 title "Sub-lethal photodynamic inactivation renders Staphylococcus aureus susceptible to silver nanoparticles" @default.
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• W1976581014 doi "https://doi.org/10.1039/c3pp50039j" @default.
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