Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976583090> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1976583090 endingPage "269" @default.
- W1976583090 startingPage "265" @default.
- W1976583090 abstract "Few trials exist regarding the antiemetic efficacy of granisetron in bone marrow transplant (BMT) recipients conditioned with high-dose chemotherapy and total body irradiation (TBI). In this single-center, open-label, prospective, trial, the antiemetic efficacy and safety of granisetron plus dexamethasone were evaluated in 26 patients conditioned with cyclophosphamide-containing regimens (the majority receiving 60 mg/kg per day on 2 consecutive days), and TBI (12 Gy divided over 4 days). Daily intravenous doses of granisetron 1 mg plus dexamethasone 10 mg were given 30 min prior to chemotherapy or radiation, and continued for 24 h after the last conditioning treatment for a median of 6 days (range 3-9). Emetic control was defined by the number of emetic episodes occurring within a 24 h period, or the requirement for rescue medication for nausea or vomiting. A total of 25 patients completed 186 evaluable treatment days. Response (emetic control by treatment days) was complete in 50% of patients, major in 48%, minor in 2%, and there were no failures. Adverse effects were minor, with diarrhea (15%), headache (14%), and constipation (11%) reported most often. Based on these results, the antiemetic regimen of granisetron plus dexamethasone appears effective and well tolerated during BMT conditioning with high-dose cyclophosphamide and TBI." @default.
- W1976583090 created "2016-06-24" @default.
- W1976583090 creator A5005544421 @default.
- W1976583090 creator A5006924930 @default.
- W1976583090 creator A5041363034 @default.
- W1976583090 creator A5044775047 @default.
- W1976583090 creator A5048913229 @default.
- W1976583090 creator A5082715731 @default.
- W1976583090 date "1999-02-01" @default.
- W1976583090 modified "2023-10-10" @default.
- W1976583090 title "Antiemetic efficacy of granisetron plus dexamethasone in bone marrow transplant patients receiving chemotherapy and total body irradiation" @default.
- W1976583090 doi "https://doi.org/10.1038/sj.bmt.1701565" @default.
- W1976583090 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10084258" @default.
- W1976583090 hasPublicationYear "1999" @default.
- W1976583090 type Work @default.
- W1976583090 sameAs 1976583090 @default.
- W1976583090 citedByCount "28" @default.
- W1976583090 countsByYear W19765830902012 @default.
- W1976583090 countsByYear W19765830902013 @default.
- W1976583090 countsByYear W19765830902015 @default.
- W1976583090 countsByYear W19765830902016 @default.
- W1976583090 countsByYear W19765830902017 @default.
- W1976583090 countsByYear W19765830902018 @default.
- W1976583090 countsByYear W19765830902019 @default.
- W1976583090 countsByYear W19765830902020 @default.
- W1976583090 countsByYear W19765830902021 @default.
- W1976583090 countsByYear W19765830902022 @default.
- W1976583090 crossrefType "journal-article" @default.
- W1976583090 hasAuthorship W1976583090A5005544421 @default.
- W1976583090 hasAuthorship W1976583090A5006924930 @default.
- W1976583090 hasAuthorship W1976583090A5041363034 @default.
- W1976583090 hasAuthorship W1976583090A5044775047 @default.
- W1976583090 hasAuthorship W1976583090A5048913229 @default.
- W1976583090 hasAuthorship W1976583090A5082715731 @default.
- W1976583090 hasBestOaLocation W19765830901 @default.
- W1976583090 hasConcept C126322002 @default.
- W1976583090 hasConcept C141071460 @default.
- W1976583090 hasConcept C197934379 @default.
- W1976583090 hasConcept C2776694085 @default.
- W1976583090 hasConcept C2776755627 @default.
- W1976583090 hasConcept C2777452722 @default.
- W1976583090 hasConcept C2778880498 @default.
- W1976583090 hasConcept C2780401358 @default.
- W1976583090 hasConcept C2780580376 @default.
- W1976583090 hasConcept C2780852908 @default.
- W1976583090 hasConcept C2780884295 @default.
- W1976583090 hasConcept C2781413609 @default.
- W1976583090 hasConcept C42219234 @default.
- W1976583090 hasConcept C71924100 @default.
- W1976583090 hasConceptScore W1976583090C126322002 @default.
- W1976583090 hasConceptScore W1976583090C141071460 @default.
- W1976583090 hasConceptScore W1976583090C197934379 @default.
- W1976583090 hasConceptScore W1976583090C2776694085 @default.
- W1976583090 hasConceptScore W1976583090C2776755627 @default.
- W1976583090 hasConceptScore W1976583090C2777452722 @default.
- W1976583090 hasConceptScore W1976583090C2778880498 @default.
- W1976583090 hasConceptScore W1976583090C2780401358 @default.
- W1976583090 hasConceptScore W1976583090C2780580376 @default.
- W1976583090 hasConceptScore W1976583090C2780852908 @default.
- W1976583090 hasConceptScore W1976583090C2780884295 @default.
- W1976583090 hasConceptScore W1976583090C2781413609 @default.
- W1976583090 hasConceptScore W1976583090C42219234 @default.
- W1976583090 hasConceptScore W1976583090C71924100 @default.
- W1976583090 hasIssue "3" @default.
- W1976583090 hasLocation W19765830901 @default.
- W1976583090 hasLocation W19765830902 @default.
- W1976583090 hasOpenAccess W1976583090 @default.
- W1976583090 hasPrimaryLocation W19765830901 @default.
- W1976583090 hasRelatedWork W1824703102 @default.
- W1976583090 hasRelatedWork W2007939615 @default.
- W1976583090 hasRelatedWork W2034199439 @default.
- W1976583090 hasRelatedWork W2039989837 @default.
- W1976583090 hasRelatedWork W2074431992 @default.
- W1976583090 hasRelatedWork W2138575646 @default.
- W1976583090 hasRelatedWork W2351639907 @default.
- W1976583090 hasRelatedWork W2399120251 @default.
- W1976583090 hasRelatedWork W4234769893 @default.
- W1976583090 hasRelatedWork W4320923492 @default.
- W1976583090 hasVolume "23" @default.
- W1976583090 isParatext "false" @default.
- W1976583090 isRetracted "false" @default.
- W1976583090 magId "1976583090" @default.
- W1976583090 workType "article" @default.