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- W1976605554 abstract "Genomic imprinting is an epigenetic phenomenon that results in differential expression of both alleles, depending on their parent of origin. We have recently identified many imprinted small non-coding RNA genes belonging to the C/D RNA and microRNA gene families, both of which are usually known to play key roles in post-transcriptional metabolism of specific genes (e.g. C/D RNAs guide ribose methylation of target RNAs while microRNAs elicit either translational repression or RNA interference). Although the functional and evolutionary significance of this association between C/D RNA genes, microRNA genes and genomic imprinting is still highly elusive, these observations provide a framework for further analysis of the potential role of small non-coding RNAs in epigenetic control." @default.
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- W1976605554 date "2004-10-01" @default.
- W1976605554 modified "2023-10-15" @default.
- W1976605554 title "Imprinted small RNA genes" @default.
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- W1976605554 doi "https://doi.org/10.1515/bc.2004.118" @default.
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