Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976623030> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1976623030 endingPage "214" @default.
- W1976623030 startingPage "210" @default.
- W1976623030 abstract "To determine the long-term efficacy of a simplification strategy in the clinical setting when used to improve adherence.Prospective study of 70 patients included in a regimen with ddI plus 3TC plus an NNRTI, after viral suppression with a PI-containing regimen, due to decreasing adherence. Adherence to PI was calculated as the percentage of doses taken last week before inclusion, and patients were stratified as high and low adherence (95% and <95% of doses).Overall, 19 patients (27%) related adherence to PI <95% at inclusion (6 patients [9%], with adherence <80%). Mean adherence improved, with only 8% of patients presenting values <95%. At 104 weeks, 88% of patients on therapy had viral load suppression, but only 43% by ITT analysis. The main cause of therapy change or withdrawal was toxicity or drug interactions (26%). Notably, 16% of patients were lost to follow-up or left therapy, especially in the group of initially low adherent (26% vs. 12%, p = .02).The use of a simplification strategy could be associated with long-term high risk of treatment failure, when used to improve adherence in the clinical setting." @default.
- W1976623030 created "2016-06-24" @default.
- W1976623030 creator A5016739033 @default.
- W1976623030 creator A5024022811 @default.
- W1976623030 creator A5030564834 @default.
- W1976623030 creator A5049114689 @default.
- W1976623030 creator A5050871700 @default.
- W1976623030 creator A5056531790 @default.
- W1976623030 creator A5057857416 @default.
- W1976623030 creator A5064873706 @default.
- W1976623030 creator A5076012773 @default.
- W1976623030 date "2006-08-01" @default.
- W1976623030 modified "2023-09-23" @default.
- W1976623030 title "Limitations of a Simplification Antiretroviral Strategy for HIV-Infected Patients with Decreasing Adherence to a Protease Inhibitor Regimen" @default.
- W1976623030 cites W2011425704 @default.
- W1976623030 cites W2017272150 @default.
- W1976623030 cites W2024438075 @default.
- W1976623030 cites W2025582221 @default.
- W1976623030 cites W2044139946 @default.
- W1976623030 cites W2057394385 @default.
- W1976623030 cites W2075091799 @default.
- W1976623030 cites W2076051895 @default.
- W1976623030 cites W2076459993 @default.
- W1976623030 cites W2081568659 @default.
- W1976623030 cites W2113643689 @default.
- W1976623030 cites W2151420123 @default.
- W1976623030 cites W2164099498 @default.
- W1976623030 cites W2318289184 @default.
- W1976623030 cites W2321852728 @default.
- W1976623030 cites W2323323105 @default.
- W1976623030 doi "https://doi.org/10.1310/hct0704-210" @default.
- W1976623030 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17065033" @default.
- W1976623030 hasPublicationYear "2006" @default.
- W1976623030 type Work @default.
- W1976623030 sameAs 1976623030 @default.
- W1976623030 citedByCount "6" @default.
- W1976623030 countsByYear W19766230302014 @default.
- W1976623030 countsByYear W19766230302015 @default.
- W1976623030 countsByYear W19766230302018 @default.
- W1976623030 crossrefType "journal-article" @default.
- W1976623030 hasAuthorship W1976623030A5016739033 @default.
- W1976623030 hasAuthorship W1976623030A5024022811 @default.
- W1976623030 hasAuthorship W1976623030A5030564834 @default.
- W1976623030 hasAuthorship W1976623030A5049114689 @default.
- W1976623030 hasAuthorship W1976623030A5050871700 @default.
- W1976623030 hasAuthorship W1976623030A5056531790 @default.
- W1976623030 hasAuthorship W1976623030A5057857416 @default.
- W1976623030 hasAuthorship W1976623030A5064873706 @default.
- W1976623030 hasAuthorship W1976623030A5076012773 @default.
- W1976623030 hasBestOaLocation W19766230301 @default.
- W1976623030 hasConcept C126322002 @default.
- W1976623030 hasConcept C140206745 @default.
- W1976623030 hasConcept C142462285 @default.
- W1976623030 hasConcept C188816634 @default.
- W1976623030 hasConcept C203014093 @default.
- W1976623030 hasConcept C2781143361 @default.
- W1976623030 hasConcept C2781413609 @default.
- W1976623030 hasConcept C2993143319 @default.
- W1976623030 hasConcept C3013748606 @default.
- W1976623030 hasConcept C71924100 @default.
- W1976623030 hasConceptScore W1976623030C126322002 @default.
- W1976623030 hasConceptScore W1976623030C140206745 @default.
- W1976623030 hasConceptScore W1976623030C142462285 @default.
- W1976623030 hasConceptScore W1976623030C188816634 @default.
- W1976623030 hasConceptScore W1976623030C203014093 @default.
- W1976623030 hasConceptScore W1976623030C2781143361 @default.
- W1976623030 hasConceptScore W1976623030C2781413609 @default.
- W1976623030 hasConceptScore W1976623030C2993143319 @default.
- W1976623030 hasConceptScore W1976623030C3013748606 @default.
- W1976623030 hasConceptScore W1976623030C71924100 @default.
- W1976623030 hasIssue "4" @default.
- W1976623030 hasLocation W19766230301 @default.
- W1976623030 hasLocation W19766230302 @default.
- W1976623030 hasOpenAccess W1976623030 @default.
- W1976623030 hasPrimaryLocation W19766230301 @default.
- W1976623030 hasRelatedWork W2020152935 @default.
- W1976623030 hasRelatedWork W2079342860 @default.
- W1976623030 hasRelatedWork W2080926698 @default.
- W1976623030 hasRelatedWork W2081418392 @default.
- W1976623030 hasRelatedWork W2282613813 @default.
- W1976623030 hasRelatedWork W2503404095 @default.
- W1976623030 hasRelatedWork W2613384466 @default.
- W1976623030 hasRelatedWork W3010145548 @default.
- W1976623030 hasRelatedWork W3212401336 @default.
- W1976623030 hasRelatedWork W4299359817 @default.
- W1976623030 hasVolume "7" @default.
- W1976623030 isParatext "false" @default.
- W1976623030 isRetracted "false" @default.
- W1976623030 magId "1976623030" @default.
- W1976623030 workType "article" @default.