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- W1976722967 abstract "1. The pesticide carbaryl induces Cl- secretion through the isolated frog skin. 2. This effect is due to the activation of both processes responsible for this phenomenon: (a) Na+/K+/2Cl- cotransport on the serosal membrane; (b) Cl- selective channels on the external membrane. 3. Cl- outflux is inhibited by bumetanide (10(-5) M) on the serosal side and by diphenylamine-2-carboxylic acid (DPC) (10(-3) M) on the external side. 4. The DPC action is not mimicked by Naproxen, a specific inhibitor of cyclooxygenase. 5. A comparison with isoprenaline, demonstrates that the carbaryl action is, paradoxically, more selective than that of isoprenaline. 6. This selectivity of carbaryl action on Cl- permeability is confirmed by the fact that, unlike isoprenaline, carbaryl does not affect the permeability of Na+ and thiourea." @default.
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- W1976722967 date "1992-10-01" @default.
- W1976722967 modified "2023-09-27" @default.
- W1976722967 title "The nature of Cl− secretion, induced by carbaryl, across the isolated skin of Rana esculenta" @default.
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- W1976722967 doi "https://doi.org/10.1016/0742-8413(92)90026-4" @default.
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