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- W1976736194 abstract "The Intelligent Mobile Lab (IMOLA) delivers metabolic and morphological parameters of living cells in a label-free and real time way. It represents a key technology for the development of new cell-based assays. Electrochemical microsensors are used to measure the extracellular acidification (pH), cellular respiration (pO <sub xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink>2</sub> ), changes in cell number and morphology (electric impedance) in a controlled environment. These parameters are closely linked to the intracellular signaling network of the living cells. They are thus likely to respond sensitively to changes in cellular vitality. A wide spectrum of cell types can be tested with the system, including adherent and suspended cells, continuous cell lines, primary cells or tissue samples. The platform is described in detail and applications in the field's oncology, toxicology and environmental monitoring are shown." @default.
- W1976736194 created "2016-06-24" @default.
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- W1976736194 date "2013-07-01" @default.
- W1976736194 modified "2023-10-14" @default.
- W1976736194 title "Label-free monitoring of whole cell vitality" @default.
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- W1976736194 doi "https://doi.org/10.1109/embc.2013.6609823" @default.
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