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- W1976757424 abstract "PEGylation, the covalent attachment of polyethylene glycol (PEG) chains to protein, isa promising method for making an efficient protein drug. Several PEGylated protein drugs, such as PEGylated interferons, are already on the market and others are presently in their clinical trials. However, the PEGylation reaction is very product specific so that generalized or platform processes for both reaction and purification have not yet been established. In the current issue of Biotechnology Journal, Günter Allmaier and colleagues report a modified microchip capillary gel electrophoresis (MCGE), which allows for a rapid separation (one minute) of PEGylated proteins of different degrees of PEGylation." @default.
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- W1976757424 date "2012-04-25" @default.
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- W1976757424 title "PEGylated protein separations: Challenges and opportunities" @default.
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- W1976757424 doi "https://doi.org/10.1002/biot.201200143" @default.
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