Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976809318> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W1976809318 endingPage "1306" @default.
- W1976809318 startingPage "1301" @default.
- W1976809318 abstract "Children treated for brain tumors with conformal radiation therapy experience preserved cognitive outcomes. Early evidence suggests that adaptive functions or independent-living skills may be spared. This longitudinal investigation prospectively examined intellectual and adaptive functioning during the first 5 years following irradiation for childhood craniopharyngioma and low-grade glioma (LGG). The effect of visual impairment on adaptive outcomes was investigated.Children with craniopharyngioma (n=62) and LGG (n=77) were treated using conformal or intensity modulated radiation therapy. The median age was 8.05 years (3.21-17.64 years) and 8.09 years (2.20-19.27 years), respectively. Serial cognitive evaluations including measures of intelligence quotient (IQ) and the Vineland Adaptive Behavior Scales (VABS) were conducted at preirradiation baseline, 6 months after treatment, and annually through 5 years. Five hundred eighty-eight evaluations were completed during the follow-up period.Baseline assessment revealed no deficits in IQ and VABS indices for children with craniopharyngioma, with significant (P<.05) longitudinal decline in VABS Communication and Socialization indices. Clinical factors associated with more rapid decline included females and preirradiation chemotherapy (interferon). The only change in VABS Daily Living Skills correlated with IQ change (r=0.34; P=.01) in children with craniopharyngioma. Children with LGG performed below population norms (P<.05) at baseline on VABS Communication, Daily Living Indices, and the Adaptive Behavior Composite, with significant (P<.05) longitudinal decline limited to VABS Communication. Older age at irradiation was a protective factor against longitudinal decline. Severe visual impairment did not independently correlate with poorer adaptive outcomes for either tumor group.There was relative sparing of postirradiation functional outcomes over time in this sample. Baseline differences in functional abilities before the initiation of irradiation suggested that other factors influence functional outcomes above and beyond the effects of irradiation." @default.
- W1976809318 created "2016-06-24" @default.
- W1976809318 creator A5006930070 @default.
- W1976809318 creator A5014542884 @default.
- W1976809318 creator A5049391890 @default.
- W1976809318 creator A5064562354 @default.
- W1976809318 creator A5075548851 @default.
- W1976809318 date "2013-04-01" @default.
- W1976809318 modified "2023-10-14" @default.
- W1976809318 title "Longitudinal Investigation of Adaptive Functioning Following Conformal Irradiation for Pediatric Craniopharyngioma and Low-Grade Glioma" @default.
- W1976809318 cites W1965516769 @default.
- W1976809318 cites W1982362383 @default.
- W1976809318 cites W2013766186 @default.
- W1976809318 cites W2035227999 @default.
- W1976809318 cites W2061406509 @default.
- W1976809318 cites W2070444599 @default.
- W1976809318 cites W2083681961 @default.
- W1976809318 cites W2088484518 @default.
- W1976809318 cites W2093655644 @default.
- W1976809318 cites W2106689678 @default.
- W1976809318 cites W2112657281 @default.
- W1976809318 cites W2119449786 @default.
- W1976809318 cites W2144778499 @default.
- W1976809318 cites W4241018099 @default.
- W1976809318 cites W4242403727 @default.
- W1976809318 doi "https://doi.org/10.1016/j.ijrobp.2012.10.031" @default.
- W1976809318 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3685870" @default.
- W1976809318 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23245284" @default.
- W1976809318 hasPublicationYear "2013" @default.
- W1976809318 type Work @default.
- W1976809318 sameAs 1976809318 @default.
- W1976809318 citedByCount "49" @default.
- W1976809318 countsByYear W19768093182014 @default.
- W1976809318 countsByYear W19768093182015 @default.
- W1976809318 countsByYear W19768093182016 @default.
- W1976809318 countsByYear W19768093182017 @default.
- W1976809318 countsByYear W19768093182018 @default.
- W1976809318 countsByYear W19768093182019 @default.
- W1976809318 countsByYear W19768093182020 @default.
- W1976809318 countsByYear W19768093182021 @default.
- W1976809318 countsByYear W19768093182022 @default.
- W1976809318 countsByYear W19768093182023 @default.
- W1976809318 crossrefType "journal-article" @default.
- W1976809318 hasAuthorship W1976809318A5006930070 @default.
- W1976809318 hasAuthorship W1976809318A5014542884 @default.
- W1976809318 hasAuthorship W1976809318A5049391890 @default.
- W1976809318 hasAuthorship W1976809318A5064562354 @default.
- W1976809318 hasAuthorship W1976809318A5075548851 @default.
- W1976809318 hasBestOaLocation W19768093182 @default.
- W1976809318 hasConcept C118552586 @default.
- W1976809318 hasConcept C122817143 @default.
- W1976809318 hasConcept C141071460 @default.
- W1976809318 hasConcept C142724271 @default.
- W1976809318 hasConcept C169900460 @default.
- W1976809318 hasConcept C187212893 @default.
- W1976809318 hasConcept C2777047896 @default.
- W1976809318 hasConcept C2777895361 @default.
- W1976809318 hasConcept C71924100 @default.
- W1976809318 hasConceptScore W1976809318C118552586 @default.
- W1976809318 hasConceptScore W1976809318C122817143 @default.
- W1976809318 hasConceptScore W1976809318C141071460 @default.
- W1976809318 hasConceptScore W1976809318C142724271 @default.
- W1976809318 hasConceptScore W1976809318C169900460 @default.
- W1976809318 hasConceptScore W1976809318C187212893 @default.
- W1976809318 hasConceptScore W1976809318C2777047896 @default.
- W1976809318 hasConceptScore W1976809318C2777895361 @default.
- W1976809318 hasConceptScore W1976809318C71924100 @default.
- W1976809318 hasIssue "5" @default.
- W1976809318 hasLocation W19768093181 @default.
- W1976809318 hasLocation W19768093182 @default.
- W1976809318 hasLocation W19768093183 @default.
- W1976809318 hasLocation W19768093184 @default.
- W1976809318 hasOpenAccess W1976809318 @default.
- W1976809318 hasPrimaryLocation W19768093181 @default.
- W1976809318 hasRelatedWork W1987825771 @default.
- W1976809318 hasRelatedWork W2005914326 @default.
- W1976809318 hasRelatedWork W2018438797 @default.
- W1976809318 hasRelatedWork W2029543626 @default.
- W1976809318 hasRelatedWork W2080703592 @default.
- W1976809318 hasRelatedWork W2182961548 @default.
- W1976809318 hasRelatedWork W2319494654 @default.
- W1976809318 hasRelatedWork W2321516769 @default.
- W1976809318 hasRelatedWork W2418933311 @default.
- W1976809318 hasRelatedWork W2989872616 @default.
- W1976809318 hasVolume "85" @default.
- W1976809318 isParatext "false" @default.
- W1976809318 isRetracted "false" @default.
- W1976809318 magId "1976809318" @default.
- W1976809318 workType "article" @default.