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- W1976877504 abstract "CD83, a maturation marker for human and mouse dendritic cells (DCs), plays a critical role in CD4+ T cell development as well as peripheral immune regulation. Here, two novel mouse anti-human CD83 monoclonal antibodies (MAbs) were prepared and their immunological characteristics were determined. Among the two MAbs, 8B4 binds to a linear epitope whereas 1E11 recognizes a conformational epitope. Cross-linking of 8B4 but not 1E11 with CD83-Ig augments the fusion protein mediated inhibition of peripheral blood mononuclear cells (PBMCs). Thus the two MAbs may be good candidates for immunoassaying and functional exploration of CD83 molecule." @default.
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- W1976877504 date "2011-06-01" @default.
- W1976877504 modified "2023-09-27" @default.
- W1976877504 title "Two Novel Monoclonal Antibodies Produced Against Human CD83 Molecule" @default.
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- W1976877504 doi "https://doi.org/10.1089/hyb.2010.0110" @default.
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