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• W1976896451 abstract "Flow cytometric analysis of eosin-5′-maleimide-labeled red blood cells has been proposed as a new method of identifying hereditary spherocytosis (HS). The aim of the present study was to analyze sensitivity and specificity of this method. Red blood cells from patients with HS (n = 58) revealed significantly lower mean channel fluorescence values than red blood cells from normal subjects (n = 110), unaffected HS family members (n = 8), and patients with other anemias (n = 44). Taking a mean channel fluorescence of 400.0 units as the threshold value identified by logistic regression, sensitivity and specificity of the test for HS were 96.6 and 99.1%, respectively. Flow cytometric analysis is a valuable screening test for the diagnosis of HS." @default.
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• W1976896451 date "2006-01-01" @default.
• W1976896451 modified "2023-09-27" @default.
• W1976896451 title "Flow Cytometry as a Diagnostic Tool for Hereditary Spherocytosis" @default.
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• W1976896451 doi "https://doi.org/10.1159/000094679" @default.
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