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• W1976929488 abstract "Female cancer patients who seek fertility preservation but cannot undergo ovarian stimulation and embryo preservation may consider 1) retrieval of immature oocytes followed by in vitro maturation (IVM) or 2) ovarian tissue cryopreservation followed by transplantation or in vitro follicle culture. Conventional IVM is carried out during the follicular phase of menstrual cycle. There is limited evidence demonstrating that immature oocyte retrieved during the luteal phase can mature in vitro and be fertilized to produce viable embryos. While in vitro follicle culture is successful in rodents, its application in nonhuman primates has made limited progress. The objective of this study was to investigate the competence of immature luteal-phase oocytes from baboon and to determine the effect of follicle-stimulating hormone (FSH) on baboon preantral follicle culture and oocyte maturation in vitro. Oocytes from small antral follicle cumulus-oocyte complexes (COCs) with multiple cumulus layers (42%) were more likely to resume meiosis and progress to metaphase II (MII) than oocytes with a single layer of cumulus cells or less (23% vs. 3%, respectively). Twenty-four percent of mature oocytes were successfully fertilized by intracytoplasmic sperm injection, and 25% of these developed to morula-stage embryos. Preantral follicles were encapsulated in fibrin-alginate-matrigel matrices and cultured to small antral stage in an FSH-independent manner. FSH negatively impacted follicle health by disrupting the integrity of oocyte and cumulus cells contact. Follicles grown in the absence of FSH produced MII oocytes with normal spindle structure. In conclusion, baboon luteal-phase COCs and oocytes from cultured preantral follicles can be matured in vitro. Oocyte meiotic competence correlated positively with the number of cumulus cell layers. This study clarifies the parameters of the follicle culture system in nonhuman primates and provides foundational data for future clinical development as a fertility preservation option for women with cancer." @default.
• W1976929488 created "2016-06-24" @default.
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• W1976929488 date "2010-12-01" @default.
• W1976929488 modified "2023-09-25" @default.
• W1976929488 title "In Vitro Oocyte Maturation and Preantral Follicle Culture from the Luteal-Phase Baboon Ovary Produce Mature Oocytes" @default.
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• W1976929488 cites W1963832918 @default.
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• W1976929488 cites W1973690432 @default.
• W1976929488 cites W1976340085 @default.
• W1976929488 cites W1990255218 @default.
• W1976929488 cites W1991238536 @default.
• W1976929488 cites W1997481556 @default.
• W1976929488 cites W2000054693 @default.
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• W1976929488 cites W2155428290 @default.
• W1976929488 cites W2155637594 @default.
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• W1976929488 doi "https://doi.org/10.1095/biolreprod.110.088674" @default.
• W1976929488 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3062036" @default.
• W1976929488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21123815" @default.
• W1976929488 hasPublicationYear "2010" @default.
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