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- W1976944384 endingPage "5241" @default.
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- W1976944384 abstract "Human herpesvirus-8 (HHV-8/KSHV) is etiologically associated with Kaposi's sarcoma (KS) and other tumors. Constitutive activation of the mitogen-activated protein kinase (MAPK) signaling pathway has been associated with a variety of tumors, including AIDS-related KS. The oncoprotein Raf is situated at a pivotal position in regulating the MAPK pathway. Hence, we analysed the effect of oncoprotein Raf on HHV-8 infectious entry into target cells. Here we report Raf expression to significantly enhance HHV-8 infection of target cells. These findings implicate a role for Raf not only in the infectious entry of HHV-8 but also in modulating KS pathogenesis." @default.
- W1976944384 created "2016-06-24" @default.
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- W1976944384 creator A5071016461 @default.
- W1976944384 date "2004-05-03" @default.
- W1976944384 modified "2023-09-30" @default.
- W1976944384 title "Raf promotes human herpesvirus-8 (HHV-8/KSHV) infection" @default.
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- W1976944384 doi "https://doi.org/10.1038/sj.onc.1207643" @default.
- W1976944384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15122343" @default.
- W1976944384 hasPublicationYear "2004" @default.
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