FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976957510> ?p ?o ?g. }

• W1976957510 endingPage "946" @default.
• W1976957510 startingPage "935" @default.
• W1976957510 abstract "Caprenin, a randomized triglyceride primarily comprising caprylic (C8:0), capric (C10:0), and behenic (C22:0) acids, was administered in a semi-purified diet to weanling Sprague-Dawley rats (25/sex/group) at dose levels of 5.23, 10.23 or 15.00% (w/w) for 91 days. Corn oil was added at 8.96, 5.91 and 3.00%, respectively, to provide essential fatty acids and digestible fat calories. Corn oil alone (12.14%) and a blend of medium-chain triglyceride (MCT) oil plus corn oil (11.21 and 3.13%, respectively) served as controls. All diets were formulated to provide about 4000 kcal/kg of diet and 26.8% of digestible calories from fat by assuming that corn oil, MCT oil, and caprenin provided 9, 7 and 5 kcal/g, respectively. Survival, clinical signs, body weight, feed consumption, feed efficiency, organ weights, organ-to-body-weight ratios, organ-to-brain-weight ratios, haematological values and clinical chemistry parameters were evaluated in all groups. Histopathology of a full complement of tissues was evaluated in the corn oil and MCT oil control groups as well as the high-dose caprenin group. Additional rats (n = 5/sex/group) were included in the study to determine whether there was marked storage of C22:0 in heart, liver or perirenal fat at the end of the 91-day feeding period. No significant differences in body weight gain were measured with the balanced caloric diets, although feed conversion efficiency was reduced in the high-dose caprenin group. No adverse effects from the ingestion of caprenin were detected, nor were significant amounts of C22:0 present in the fat extracted from the selected fat depot sites. These results establish a no-observable-adverse-effect level (NOAEL) of more than 15% (w/w) caprenin in the diet (or more than 83% of total dietary fat), which is equal to a mean exposure level of more than 13.2 g/kg/day for male rats and more than 14.6 g/kg/day for female rats." @default.
• W1976957510 created "2016-06-24" @default.
• W1976957510 creator A5044958404 @default.
• W1976957510 creator A5046553788 @default.
• W1976957510 creator A5058304563 @default.
• W1976957510 creator A5086538080 @default.
• W1976957510 date "1993-12-01" @default.
• W1976957510 modified "2023-10-01" @default.
• W1976957510 title "A 91-day feeding study in rats with caprenin" @default.
• W1976957510 cites W107286449 @default.
• W1976957510 cites W1539835752 @default.
• W1976957510 cites W1552927763 @default.
• W1976957510 cites W1571006238 @default.
• W1976957510 cites W1584167399 @default.
• W1976957510 cites W1847853779 @default.
• W1976957510 cites W1923410671 @default.
• W1976957510 cites W1934173988 @default.
• W1976957510 cites W1963984402 @default.
• W1976957510 cites W1978551418 @default.
• W1976957510 cites W1980493083 @default.
• W1976957510 cites W1986550718 @default.
• W1976957510 cites W1988338512 @default.
• W1976957510 cites W1989633326 @default.
• W1976957510 cites W1992355225 @default.
• W1976957510 cites W1996986754 @default.
• W1976957510 cites W1997358247 @default.
• W1976957510 cites W1997788961 @default.
• W1976957510 cites W2001147479 @default.
• W1976957510 cites W2032638458 @default.
• W1976957510 cites W2035206177 @default.
• W1976957510 cites W2036637026 @default.
• W1976957510 cites W2046499923 @default.
• W1976957510 cites W2050198891 @default.
• W1976957510 cites W2054525632 @default.
• W1976957510 cites W2057762797 @default.
• W1976957510 cites W2067131467 @default.
• W1976957510 cites W2080437118 @default.
• W1976957510 cites W2082529890 @default.
• W1976957510 cites W2100142196 @default.
• W1976957510 cites W2106298549 @default.
• W1976957510 cites W2130740704 @default.
• W1976957510 cites W2146824312 @default.
• W1976957510 cites W2148765524 @default.
• W1976957510 cites W2151164099 @default.
• W1976957510 cites W2167143733 @default.
• W1976957510 cites W2252459413 @default.
• W1976957510 cites W2322126628 @default.
• W1976957510 cites W2407440048 @default.
• W1976957510 cites W2423536192 @default.
• W1976957510 cites W2460686841 @default.
• W1976957510 cites W56023647 @default.
• W1976957510 doi "https://doi.org/10.1016/0278-6915(93)90002-g" @default.
• W1976957510 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8282277" @default.
• W1976957510 hasPublicationYear "1993" @default.
• W1976957510 type Work @default.
• W1976957510 sameAs 1976957510 @default.
• W1976957510 citedByCount "16" @default.
• W1976957510 countsByYear W19769575102017 @default.
• W1976957510 countsByYear W19769575102020 @default.
• W1976957510 countsByYear W19769575102022 @default.
• W1976957510 crossrefType "journal-article" @default.
• W1976957510 hasAuthorship W1976957510A5044958404 @default.
• W1976957510 hasAuthorship W1976957510A5046553788 @default.
• W1976957510 hasAuthorship W1976957510A5058304563 @default.
• W1976957510 hasAuthorship W1976957510A5086538080 @default.
• W1976957510 hasConcept C134018914 @default.
• W1976957510 hasConcept C140793950 @default.
• W1976957510 hasConcept C147583825 @default.
• W1976957510 hasConcept C185592680 @default.
• W1976957510 hasConcept C2778163477 @default.
• W1976957510 hasConcept C2778206080 @default.
• W1976957510 hasConcept C2778433245 @default.
• W1976957510 hasConcept C2778913445 @default.
• W1976957510 hasConcept C2780320433 @default.
• W1976957510 hasConcept C31903555 @default.
• W1976957510 hasConcept C40438245 @default.
• W1976957510 hasConcept C55493867 @default.
• W1976957510 hasConcept C86803240 @default.
• W1976957510 hasConceptScore W1976957510C134018914 @default.
• W1976957510 hasConceptScore W1976957510C140793950 @default.
• W1976957510 hasConceptScore W1976957510C147583825 @default.
• W1976957510 hasConceptScore W1976957510C185592680 @default.
• W1976957510 hasConceptScore W1976957510C2778163477 @default.
• W1976957510 hasConceptScore W1976957510C2778206080 @default.
• W1976957510 hasConceptScore W1976957510C2778433245 @default.
• W1976957510 hasConceptScore W1976957510C2778913445 @default.
• W1976957510 hasConceptScore W1976957510C2780320433 @default.
• W1976957510 hasConceptScore W1976957510C31903555 @default.
• W1976957510 hasConceptScore W1976957510C40438245 @default.
• W1976957510 hasConceptScore W1976957510C55493867 @default.
• W1976957510 hasConceptScore W1976957510C86803240 @default.
• W1976957510 hasIssue "12" @default.
• W1976957510 hasLocation W19769575101 @default.
• W1976957510 hasLocation W19769575102 @default.
• W1976957510 hasOpenAccess W1976957510 @default.
• W1976957510 hasPrimaryLocation W19769575101 @default.
• W1976957510 hasRelatedWork W1494512381 @default.
• W1976957510 hasRelatedWork W1588055252 @default.

• next