FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976989712> ?p ?o ?g. }

• W1976989712 endingPage "???" @default.
• W1976989712 startingPage "071106220754002" @default.
• W1976989712 abstract "OBJECTIVE To use a large population-based case-control study to test the association between the common genetic variant rs743572 (−34 T to C), prostate cancer risk and circulating levels of several hormones. SUBJECTS AND METHODS A previous meta-analysis concluded that reported associations between rs743572 in the promoter of CYP17A1 and prostate cancer risk might reflect publication bias, but a few recent studies reported associations with prostate cancer risk and data suggesting that rs743572 is functional. We genotyped 824 prostate cancer cases and 737 population-based controls, and applied unconditional logistic regression to estimate the association between rs743572 and prostate cancer risk. We also used linear regression of transformed testosterone, androstanediol glucuronide, dehydroepiandrosterone sulphate, androstenedione, sex hormone-binding globulin and oestradiol (circulating levels) measured for controls, to estimate the association between these levels and rs743572. The linear models were adjusted for age and laboratory batch. RESULTS Men with different genotypes had similar circulating levels of all the hormones measured (all P < 0.05). In the case-control comparison using unconditional unadjusted logistic regression, the odds ratios (95% confidence interval) for prostate cancer were 1.07 (0.87–1.32) and 0.94 (0.71–1.25) for the dominant and recessive models, respectively, and for the co-dominant model, 1.10 (0.88–1.36) and 0.99 (0.73–1.35) for carriers of one or two copies of the C allele, respectively. There was no evidence of heterogeneity in the odds ratios by tumour stage (all P > 0.3) and grade (all P > 0.3). CONCLUSION The results of the present study are consistent with the conclusions of the previous meta-analysis, and suggest that rs743572 has no role in the risk of prostate cancer for men of Caucasian origin." @default.
• W1976989712 created "2016-06-24" @default.
• W1976989712 creator A5011749185 @default.
• W1976989712 creator A5018723032 @default.
• W1976989712 creator A5019133187 @default.
• W1976989712 creator A5023667273 @default.
• W1976989712 creator A5025920550 @default.
• W1976989712 creator A5027248689 @default.
• W1976989712 creator A5030507591 @default.
• W1976989712 creator A5034946189 @default.
• W1976989712 creator A5041210425 @default.
• W1976989712 creator A5052288729 @default.
• W1976989712 creator A5074633720 @default.
• W1976989712 creator A5089741432 @default.
• W1976989712 date "2007-11-06" @default.
• W1976989712 modified "2023-10-16" @default.
• W1976989712 title "The rs743572 common variant in the promoter of CYP17A1 is not associated with prostate cancer risk or circulating hormonal levels" @default.
• W1976989712 cites W1967895736 @default.
• W1976989712 cites W2024506467 @default.
• W1976989712 cites W2034428861 @default.
• W1976989712 cites W2035758530 @default.
• W1976989712 cites W2061472576 @default.
• W1976989712 cites W2083518663 @default.
• W1976989712 cites W2091056475 @default.
• W1976989712 cites W2095135250 @default.
• W1976989712 cites W2096892156 @default.
• W1976989712 cites W2097846180 @default.
• W1976989712 cites W2124613341 @default.
• W1976989712 cites W2292466962 @default.
• W1976989712 doi "https://doi.org/10.1111/j.1464-410x.2007.07272.x" @default.
• W1976989712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17986287" @default.
• W1976989712 hasPublicationYear "2007" @default.
• W1976989712 type Work @default.
• W1976989712 sameAs 1976989712 @default.
• W1976989712 citedByCount "10" @default.
• W1976989712 countsByYear W19769897122012 @default.
• W1976989712 countsByYear W19769897122013 @default.
• W1976989712 countsByYear W19769897122014 @default.
• W1976989712 countsByYear W19769897122015 @default.
• W1976989712 countsByYear W19769897122020 @default.
• W1976989712 countsByYear W19769897122023 @default.
• W1976989712 crossrefType "journal-article" @default.
• W1976989712 hasAuthorship W1976989712A5011749185 @default.
• W1976989712 hasAuthorship W1976989712A5018723032 @default.
• W1976989712 hasAuthorship W1976989712A5019133187 @default.
• W1976989712 hasAuthorship W1976989712A5023667273 @default.
• W1976989712 hasAuthorship W1976989712A5025920550 @default.
• W1976989712 hasAuthorship W1976989712A5027248689 @default.
• W1976989712 hasAuthorship W1976989712A5030507591 @default.
• W1976989712 hasAuthorship W1976989712A5034946189 @default.
• W1976989712 hasAuthorship W1976989712A5041210425 @default.
• W1976989712 hasAuthorship W1976989712A5052288729 @default.
• W1976989712 hasAuthorship W1976989712A5074633720 @default.
• W1976989712 hasAuthorship W1976989712A5089741432 @default.
• W1976989712 hasConcept C121608353 @default.
• W1976989712 hasConcept C126322002 @default.
• W1976989712 hasConcept C134018914 @default.
• W1976989712 hasConcept C143998085 @default.
• W1976989712 hasConcept C146304588 @default.
• W1976989712 hasConcept C156957248 @default.
• W1976989712 hasConcept C2776235491 @default.
• W1976989712 hasConcept C2779279991 @default.
• W1976989712 hasConcept C2780192828 @default.
• W1976989712 hasConcept C2908647359 @default.
• W1976989712 hasConcept C29456083 @default.
• W1976989712 hasConcept C44249647 @default.
• W1976989712 hasConcept C71924100 @default.
• W1976989712 hasConcept C99454951 @default.
• W1976989712 hasConceptScore W1976989712C121608353 @default.
• W1976989712 hasConceptScore W1976989712C126322002 @default.
• W1976989712 hasConceptScore W1976989712C134018914 @default.
• W1976989712 hasConceptScore W1976989712C143998085 @default.
• W1976989712 hasConceptScore W1976989712C146304588 @default.
• W1976989712 hasConceptScore W1976989712C156957248 @default.
• W1976989712 hasConceptScore W1976989712C2776235491 @default.
• W1976989712 hasConceptScore W1976989712C2779279991 @default.
• W1976989712 hasConceptScore W1976989712C2780192828 @default.
• W1976989712 hasConceptScore W1976989712C2908647359 @default.
• W1976989712 hasConceptScore W1976989712C29456083 @default.
• W1976989712 hasConceptScore W1976989712C44249647 @default.
• W1976989712 hasConceptScore W1976989712C71924100 @default.
• W1976989712 hasConceptScore W1976989712C99454951 @default.
• W1976989712 hasIssue "0" @default.
• W1976989712 hasLocation W19769897121 @default.
• W1976989712 hasLocation W19769897122 @default.
• W1976989712 hasOpenAccess W1976989712 @default.
• W1976989712 hasPrimaryLocation W19769897121 @default.
• W1976989712 hasRelatedWork W1988486434 @default.
• W1976989712 hasRelatedWork W1998113603 @default.
• W1976989712 hasRelatedWork W1999611386 @default.
• W1976989712 hasRelatedWork W1999831221 @default.
• W1976989712 hasRelatedWork W2027237635 @default.
• W1976989712 hasRelatedWork W2036308844 @default.
• W1976989712 hasRelatedWork W2081677525 @default.
• W1976989712 hasRelatedWork W2082603313 @default.
• W1976989712 hasRelatedWork W2100202028 @default.
• W1976989712 hasRelatedWork W2317313649 @default.
• W1976989712 hasVolume "0" @default.

• next