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- W1976992912 abstract "Eating behavior changes under stress, i.e. during high HPA-axis activation. Assessment of effects of high versus low HPA-axis activation on liking and wanting related brain signaling in relevant regions. 15 female subjects (21.5 ± 0.4 years, BMI = 22.2 ± 0.4) completed fMRI scans on 2 days, in a fasted as well as a satiated condition on each day. The days were sorted by HPA-axis activation, resulting in two sufficiently separated HPA-axis states which were statistically confirmed (p < .05). During scans, subjects rated liking and wanting for food images; wanting indicated food choice for the subsequent meal. Energy-intake, hunger and fullness were additionally recorded. Hunger changed significantly over the meal (p < .001). Energy intake was lower during the second meal (p < .001). Behavioral wanting was lower after breakfast (p < .01), behavioral liking did not change. During low HPA-activation, liking task related signaling (TRS) pre-meal in the anterior insula predicted behavioral liking, wanting TRS in the anterior insula, nucleus accumbens and thalamus predicted behavioral wanting. During high HPA-activation, these relationships were not present pre-meal, but post-meal behavioral liking was predicted in the nucleus accumbens and wanting in the caudate. High HPA-axis activation disrupted and redirected the connection of behavioral liking/wanting with the specifically associated brain signaling in relevant regions." @default.
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- W1976992912 date "2012-01-01" @default.
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- W1976992912 title "High HPA-axis activation disrupts the link between liking and wanting with liking and wanting related brain signaling" @default.
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- W1976992912 doi "https://doi.org/10.1016/j.physbeh.2011.08.015" @default.
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