FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977016714> ?p ?o ?g. }

• W1977016714 endingPage "10" @default.
• W1977016714 startingPage "6" @default.
• W1977016714 abstract "Excitotoxicity by which excitatory amino acid induces neuronal cell death may underlie mechanisms of neurodegenerative diseases. We previously found that c-fos is critically involved in neuronal excitability and survival. Mice that carry hippocampal mutations of c-fos exhibited hyper-excitability, hyper-excitotoxicity and higher mortality in kainic acid (KA)-induced seizures compared to wild-type mice. To further understand the neuroprotective signal transduction pathways regulated by c-fos in the hippocampal formation, we identified 172 genes that are either regulated by KA or are differentially expressed in wild-type and hippocampal-specific c-fos mutant mice using cDNA microarrays. One gene encodes the neuropeptide Y (NPY). We confirmed that c-fos regulates the expression of NPY by using immunohistochemistry. We found that c-fos is critical in up-regulation of NPY expression in the granule cell layer of dentate gyrus in response to KA administration. As NPY is an important endogenous anti-epileptic agent, our result is consistent with a hypothesis that the neuroprotective function of c-fos is mediated in part by regulation of NPY expression." @default.
• W1977016714 created "2016-06-24" @default.
• W1977016714 creator A5004464435 @default.
• W1977016714 creator A5011050795 @default.
• W1977016714 creator A5016316795 @default.
• W1977016714 creator A5017582966 @default.
• W1977016714 creator A5064856328 @default.
• W1977016714 creator A5069092697 @default.
• W1977016714 creator A5072284526 @default.
• W1977016714 date "2004-06-01" @default.
• W1977016714 modified "2023-09-29" @default.
• W1977016714 title "c-fos regulates neuropeptide Y expression in mouse dentate gyrus" @default.
• W1977016714 cites W1488959508 @default.
• W1977016714 cites W1971046097 @default.
• W1977016714 cites W1981675681 @default.
• W1977016714 cites W1983633304 @default.
• W1977016714 cites W2016192281 @default.
• W1977016714 cites W2021253208 @default.
• W1977016714 cites W2022521115 @default.
• W1977016714 cites W2034382807 @default.
• W1977016714 cites W2038068698 @default.
• W1977016714 cites W2048688619 @default.
• W1977016714 cites W2050695642 @default.
• W1977016714 cites W2058744360 @default.
• W1977016714 cites W2089364308 @default.
• W1977016714 cites W2092976778 @default.
• W1977016714 cites W2093710529 @default.
• W1977016714 cites W2126027530 @default.
• W1977016714 cites W2156566914 @default.
• W1977016714 doi "https://doi.org/10.1016/j.neulet.2004.02.020" @default.
• W1977016714 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15157984" @default.
• W1977016714 hasPublicationYear "2004" @default.
• W1977016714 type Work @default.
• W1977016714 sameAs 1977016714 @default.
• W1977016714 citedByCount "19" @default.
• W1977016714 countsByYear W19770167142012 @default.
• W1977016714 countsByYear W19770167142013 @default.
• W1977016714 countsByYear W19770167142014 @default.
• W1977016714 countsByYear W19770167142015 @default.
• W1977016714 countsByYear W19770167142017 @default.
• W1977016714 countsByYear W19770167142018 @default.
• W1977016714 countsByYear W19770167142020 @default.
• W1977016714 crossrefType "journal-article" @default.
• W1977016714 hasAuthorship W1977016714A5004464435 @default.
• W1977016714 hasAuthorship W1977016714A5011050795 @default.
• W1977016714 hasAuthorship W1977016714A5016316795 @default.
• W1977016714 hasAuthorship W1977016714A5017582966 @default.
• W1977016714 hasAuthorship W1977016714A5064856328 @default.
• W1977016714 hasAuthorship W1977016714A5069092697 @default.
• W1977016714 hasAuthorship W1977016714A5072284526 @default.
• W1977016714 hasConcept C104317684 @default.
• W1977016714 hasConcept C118303440 @default.
• W1977016714 hasConcept C126322002 @default.
• W1977016714 hasConcept C134018914 @default.
• W1977016714 hasConcept C148762608 @default.
• W1977016714 hasConcept C150194340 @default.
• W1977016714 hasConcept C169760540 @default.
• W1977016714 hasConcept C170493617 @default.
• W1977016714 hasConcept C25498285 @default.
• W1977016714 hasConcept C2776108384 @default.
• W1977016714 hasConcept C2776464000 @default.
• W1977016714 hasConcept C2778888523 @default.
• W1977016714 hasConcept C2779555244 @default.
• W1977016714 hasConcept C2781012912 @default.
• W1977016714 hasConcept C54355233 @default.
• W1977016714 hasConcept C61174792 @default.
• W1977016714 hasConcept C71924100 @default.
• W1977016714 hasConcept C86803240 @default.
• W1977016714 hasConcept C93984277 @default.
• W1977016714 hasConcept C95444343 @default.
• W1977016714 hasConceptScore W1977016714C104317684 @default.
• W1977016714 hasConceptScore W1977016714C118303440 @default.
• W1977016714 hasConceptScore W1977016714C126322002 @default.
• W1977016714 hasConceptScore W1977016714C134018914 @default.
• W1977016714 hasConceptScore W1977016714C148762608 @default.
• W1977016714 hasConceptScore W1977016714C150194340 @default.
• W1977016714 hasConceptScore W1977016714C169760540 @default.
• W1977016714 hasConceptScore W1977016714C170493617 @default.
• W1977016714 hasConceptScore W1977016714C25498285 @default.
• W1977016714 hasConceptScore W1977016714C2776108384 @default.
• W1977016714 hasConceptScore W1977016714C2776464000 @default.
• W1977016714 hasConceptScore W1977016714C2778888523 @default.
• W1977016714 hasConceptScore W1977016714C2779555244 @default.
• W1977016714 hasConceptScore W1977016714C2781012912 @default.
• W1977016714 hasConceptScore W1977016714C54355233 @default.
• W1977016714 hasConceptScore W1977016714C61174792 @default.
• W1977016714 hasConceptScore W1977016714C71924100 @default.
• W1977016714 hasConceptScore W1977016714C86803240 @default.
• W1977016714 hasConceptScore W1977016714C93984277 @default.
• W1977016714 hasConceptScore W1977016714C95444343 @default.
• W1977016714 hasIssue "1" @default.
• W1977016714 hasLocation W19770167141 @default.
• W1977016714 hasLocation W19770167142 @default.
• W1977016714 hasOpenAccess W1977016714 @default.
• W1977016714 hasPrimaryLocation W19770167141 @default.
• W1977016714 hasRelatedWork W1577503601 @default.
• W1977016714 hasRelatedWork W1964681304 @default.
• W1977016714 hasRelatedWork W1968216099 @default.

• next