FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977028961> ?p ?o ?g. }

• W1977028961 endingPage "4655" @default.
• W1977028961 startingPage "4646" @default.
• W1977028961 abstract "One known and two novel antioxidant compounds have been isolated from bamboo (Phyllostachys edulis). The butanol-soluble extract of the bamboo leaves was found to have a significant antioxidant activity, as measured by scavenging the stable 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical and the superoxide anion radical (O(2)(-)) in the xanthine/xanthine oxidase assay system. Antioxidant activity-directed fractionation of the extract led to the isolation and characterization of three structural isomeric chlorogenic acid derivatives: 3-O-(3'-methylcaffeoyl)quinic acid (1), 5-O-caffeoyl-4-methylquinic acid (2), and 3-O-caffeoyl-1-methylquinic acid (3). Compounds 2 and 3 were isolated and characterized for the first time from the natural products. In the DPPH scavenging assay as well as in the iron-induced rat microsomal lipid peroxidation system, compounds 2 (IC(50) = 8.8 and 19.2 microM) and 3 (IC(50) = 6.9 and 14.6 microM) showed approximately 2-4 times higher antioxidant activity than did chlorogenic acid (IC(50) = 12.3 and 28.3 microM) and other related hydroxycinnamates such as caffeic acid (IC(50) =13.7 and 25.5 microM) and ferulic acid (IC(50) = 36.5 and 56.9 microM). Among the three compounds, compound 1 yielded the weakest antioxidant activity, and the DPPH scavenging and lipid peroxidation inhibitory activity (IC(50) = 16.0 and 29.8 microM) was lower than those of chlorogenic and caffeic acids. All three compounds exhibited both superoxide scavenging activities and inhibitory effects on xanthine oxidase. Their superoxide anion (O(2)(-)) scavenging activities (IC(50) = 1, 4.3 microM; 2, 2.8 microM; and 3, 1.2 microM) were markedly stronger than those of ascorbic acid (IC(50) = 56.0 microM), alpha-tocopherol (IC(50) > 100 microM), and other test compounds, although their inhibition effects on xanthine oxidase may contribute to the potent scavenging activity. alpha-Tocopherol exerted a significant inhibitory effect (65.5% of the control) on superoxide generation in 12-O-tetradecanoylphorbol-13-acetate-induced human promyelocytic leukemia HL-60 cells, and compound 3 showed moderate activity (36.0%). On the other hand, other compounds including 1, 2, chlorogenic acid, and other antioxidants were weakly active (24.8-10.1%) in the suppression of superoxide generation." @default.
• W1977028961 created "2016-06-24" @default.
• W1977028961 creator A5001177583 @default.
• W1977028961 creator A5006487986 @default.
• W1977028961 creator A5090033210 @default.
• W1977028961 date "2001-09-12" @default.
• W1977028961 modified "2023-10-10" @default.
• W1977028961 title "Identification and Antioxidant Activity of Novel Chlorogenic Acid Derivatives from Bamboo (<i>Phyllostachys edulis</i>)" @default.
• W1977028961 cites W1991102999 @default.
• W1977028961 cites W1999382806 @default.
• W1977028961 cites W2004297939 @default.
• W1977028961 cites W2011514657 @default.
• W1977028961 cites W2017039268 @default.
• W1977028961 cites W2029842272 @default.
• W1977028961 cites W2036684416 @default.
• W1977028961 cites W2047880042 @default.
• W1977028961 cites W2048560794 @default.
• W1977028961 cites W2055377214 @default.
• W1977028961 cites W2057476398 @default.
• W1977028961 cites W2070934089 @default.
• W1977028961 cites W2074928249 @default.
• W1977028961 cites W2082821204 @default.
• W1977028961 cites W2091336803 @default.
• W1977028961 cites W2114412501 @default.
• W1977028961 cites W2119558428 @default.
• W1977028961 cites W2233474005 @default.
• W1977028961 cites W3132538541 @default.
• W1977028961 cites W62967950 @default.
• W1977028961 cites W2015209351 @default.
• W1977028961 doi "https://doi.org/10.1021/jf010514x" @default.
• W1977028961 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11600002" @default.
• W1977028961 hasPublicationYear "2001" @default.
• W1977028961 type Work @default.
• W1977028961 sameAs 1977028961 @default.
• W1977028961 citedByCount "261" @default.
• W1977028961 countsByYear W19770289612012 @default.
• W1977028961 countsByYear W19770289612013 @default.
• W1977028961 countsByYear W19770289612014 @default.
• W1977028961 countsByYear W19770289612015 @default.
• W1977028961 countsByYear W19770289612016 @default.
• W1977028961 countsByYear W19770289612017 @default.
• W1977028961 countsByYear W19770289612018 @default.
• W1977028961 countsByYear W19770289612019 @default.
• W1977028961 countsByYear W19770289612020 @default.
• W1977028961 countsByYear W19770289612021 @default.
• W1977028961 countsByYear W19770289612022 @default.
• W1977028961 countsByYear W19770289612023 @default.
• W1977028961 crossrefType "journal-article" @default.
• W1977028961 hasAuthorship W1977028961A5001177583 @default.
• W1977028961 hasAuthorship W1977028961A5006487986 @default.
• W1977028961 hasAuthorship W1977028961A5090033210 @default.
• W1977028961 hasConcept C181199279 @default.
• W1977028961 hasConcept C185592680 @default.
• W1977028961 hasConcept C2778004101 @default.
• W1977028961 hasConcept C2778102346 @default.
• W1977028961 hasConcept C2778224086 @default.
• W1977028961 hasConcept C2779470414 @default.
• W1977028961 hasConcept C2780117898 @default.
• W1977028961 hasConcept C2780213334 @default.
• W1977028961 hasConcept C2780795997 @default.
• W1977028961 hasConcept C2780809830 @default.
• W1977028961 hasConcept C2780829032 @default.
• W1977028961 hasConcept C2781401929 @default.
• W1977028961 hasConcept C31903555 @default.
• W1977028961 hasConcept C543025807 @default.
• W1977028961 hasConcept C55493867 @default.
• W1977028961 hasConceptScore W1977028961C181199279 @default.
• W1977028961 hasConceptScore W1977028961C185592680 @default.
• W1977028961 hasConceptScore W1977028961C2778004101 @default.
• W1977028961 hasConceptScore W1977028961C2778102346 @default.
• W1977028961 hasConceptScore W1977028961C2778224086 @default.
• W1977028961 hasConceptScore W1977028961C2779470414 @default.
• W1977028961 hasConceptScore W1977028961C2780117898 @default.
• W1977028961 hasConceptScore W1977028961C2780213334 @default.
• W1977028961 hasConceptScore W1977028961C2780795997 @default.
• W1977028961 hasConceptScore W1977028961C2780809830 @default.
• W1977028961 hasConceptScore W1977028961C2780829032 @default.
• W1977028961 hasConceptScore W1977028961C2781401929 @default.
• W1977028961 hasConceptScore W1977028961C31903555 @default.
• W1977028961 hasConceptScore W1977028961C543025807 @default.
• W1977028961 hasConceptScore W1977028961C55493867 @default.
• W1977028961 hasIssue "10" @default.
• W1977028961 hasLocation W19770289611 @default.
• W1977028961 hasLocation W19770289612 @default.
• W1977028961 hasOpenAccess W1977028961 @default.
• W1977028961 hasPrimaryLocation W19770289611 @default.
• W1977028961 hasRelatedWork W2012317245 @default.
• W1977028961 hasRelatedWork W2013517796 @default.
• W1977028961 hasRelatedWork W2059359543 @default.
• W1977028961 hasRelatedWork W2064370066 @default.
• W1977028961 hasRelatedWork W2082798463 @default.
• W1977028961 hasRelatedWork W2156716051 @default.
• W1977028961 hasRelatedWork W2349339739 @default.
• W1977028961 hasRelatedWork W2350344210 @default.
• W1977028961 hasRelatedWork W2371655707 @default.
• W1977028961 hasRelatedWork W2376786073 @default.
• W1977028961 hasVolume "49" @default.
• W1977028961 isParatext "false" @default.

• next