FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977034933> ?p ?o ?g. }

• W1977034933 endingPage "25" @default.
• W1977034933 startingPage "18" @default.
• W1977034933 abstract "The aim of this study was to investigate whether the application of an Infrared Pulsed Laser Device (IPLD) photo-induced significant cytomorphologic changes during the monitoring of advanced cancer patients participating in a phase I clinical trial.Patients were irradiated with an IPLD (904 nm pulsed at 3 MHz) under a one-dose, one-schedule, and one-procedure design. Total daily dose consisted of a Radiant Exposure of 4.5x10(5) J/m(2). Thirty-one tissue samples from eleven patients with progressive solid neoplastic diseases (TNM IV, UICC) were obtained at three intervals: Time 0 (15-90 days pre-treatment, n=11); Time I (2-5 months post-treatment; n=11); Time II (6-12 months post-treatment, n=09). Three blinded pathologists evaluated samples; scores were determined by consensus. Data were evaluated by using the Wilcoxon matched-pairs signed-rank test and Spearman rank correlation coefficient. The level of statistical significance was alpha=0.05.Increased apoptosis (Time I, P<0.003; Time II, P<0.007), necrosis (Time I, NS; Time II, P<0.01), cytoplasmic vacuoles (Time I, P<0.03; Time II, P<0.02), and nuclear vacuoles (Time I, NS; Time II, P<0.01), reduced cell size (Time I, P<0.007; Time II, P<0.01) and intercellular adhesion (Time I, P<0.01; Time II, P<0.02) were present in neoplastic cells after IPLD treatment. No apparent changes were noted in non-neoplastic cells. The Spearman rank correlation coefficient between apoptosis, necrosis, nuclear vacuoles, cytoplasmatic vacuoles, intercellular adhesion, and cell size was positive and highly significant (P<0.006).Although further research is necessary, our preliminary results support the novel possibility that the IPLD photo-induces chaotic dynamics that modulate complex physiologically reparative bioeffects." @default.
• W1977034933 created "2016-06-24" @default.
• W1977034933 creator A5007263704 @default.
• W1977034933 creator A5063993415 @default.
• W1977034933 creator A5068861825 @default.
• W1977034933 creator A5069961410 @default.
• W1977034933 date "2002-01-01" @default.
• W1977034933 modified "2023-10-17" @default.
• W1977034933 title "Photo-induced cytomorphologic changes in an advanced cancer phase I clinical trial" @default.
• W1977034933 cites W1500228115 @default.
• W1977034933 cites W1563494356 @default.
• W1977034933 cites W1627195251 @default.
• W1977034933 cites W1661967651 @default.
• W1977034933 cites W1787366216 @default.
• W1977034933 cites W1967061768 @default.
• W1977034933 cites W1971103030 @default.
• W1977034933 cites W1972779758 @default.
• W1977034933 cites W1978240169 @default.
• W1977034933 cites W1984335380 @default.
• W1977034933 cites W1996385467 @default.
• W1977034933 cites W2000407409 @default.
• W1977034933 cites W2009377846 @default.
• W1977034933 cites W2011438179 @default.
• W1977034933 cites W2014467121 @default.
• W1977034933 cites W2014845290 @default.
• W1977034933 cites W2019740661 @default.
• W1977034933 cites W2021376551 @default.
• W1977034933 cites W2026892879 @default.
• W1977034933 cites W2027904286 @default.
• W1977034933 cites W2037170319 @default.
• W1977034933 cites W2037908764 @default.
• W1977034933 cites W2052569700 @default.
• W1977034933 cites W2052766715 @default.
• W1977034933 cites W2052853635 @default.
• W1977034933 cites W2058096164 @default.
• W1977034933 cites W2065372326 @default.
• W1977034933 cites W2069777912 @default.
• W1977034933 cites W2084018073 @default.
• W1977034933 cites W2084470802 @default.
• W1977034933 cites W2088046237 @default.
• W1977034933 cites W2095037097 @default.
• W1977034933 cites W2113396371 @default.
• W1977034933 cites W2114811530 @default.
• W1977034933 cites W2115220637 @default.
• W1977034933 cites W2116267801 @default.
• W1977034933 cites W2125644189 @default.
• W1977034933 cites W2127883090 @default.
• W1977034933 cites W2128729627 @default.
• W1977034933 cites W2137952321 @default.
• W1977034933 cites W2138867387 @default.
• W1977034933 cites W2155694261 @default.
• W1977034933 cites W2321019905 @default.
• W1977034933 cites W2940231302 @default.
• W1977034933 cites W4211003445 @default.
• W1977034933 cites W4238595626 @default.
• W1977034933 cites W4252263686 @default.
• W1977034933 doi "https://doi.org/10.1002/lsm.10017" @default.
• W1977034933 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11857599" @default.
• W1977034933 hasPublicationYear "2002" @default.
• W1977034933 type Work @default.
• W1977034933 sameAs 1977034933 @default.
• W1977034933 citedByCount "22" @default.
• W1977034933 countsByYear W19770349332012 @default.
• W1977034933 countsByYear W19770349332013 @default.
• W1977034933 countsByYear W19770349332015 @default.
• W1977034933 countsByYear W19770349332016 @default.
• W1977034933 countsByYear W19770349332017 @default.
• W1977034933 countsByYear W19770349332019 @default.
• W1977034933 countsByYear W19770349332020 @default.
• W1977034933 countsByYear W19770349332021 @default.
• W1977034933 countsByYear W19770349332022 @default.
• W1977034933 crossrefType "journal-article" @default.
• W1977034933 hasAuthorship W1977034933A5007263704 @default.
• W1977034933 hasAuthorship W1977034933A5063993415 @default.
• W1977034933 hasAuthorship W1977034933A5068861825 @default.
• W1977034933 hasAuthorship W1977034933A5069961410 @default.
• W1977034933 hasConcept C101601086 @default.
• W1977034933 hasConcept C119857082 @default.
• W1977034933 hasConcept C121608353 @default.
• W1977034933 hasConcept C126322002 @default.
• W1977034933 hasConcept C126894567 @default.
• W1977034933 hasConcept C12868164 @default.
• W1977034933 hasConcept C142724271 @default.
• W1977034933 hasConcept C185592680 @default.
• W1977034933 hasConcept C190283241 @default.
• W1977034933 hasConcept C206041023 @default.
• W1977034933 hasConcept C2775934546 @default.
• W1977034933 hasConcept C2989005 @default.
• W1977034933 hasConcept C41008148 @default.
• W1977034933 hasConcept C503630168 @default.
• W1977034933 hasConcept C55493867 @default.
• W1977034933 hasConcept C71924100 @default.
• W1977034933 hasConceptScore W1977034933C101601086 @default.
• W1977034933 hasConceptScore W1977034933C119857082 @default.
• W1977034933 hasConceptScore W1977034933C121608353 @default.
• W1977034933 hasConceptScore W1977034933C126322002 @default.
• W1977034933 hasConceptScore W1977034933C126894567 @default.
• W1977034933 hasConceptScore W1977034933C12868164 @default.

• next