FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977047462> ?p ?o ?g. }

• W1977047462 endingPage "799" @default.
• W1977047462 startingPage "787" @default.
• W1977047462 abstract "Prader-Willi syndrome is a genetic disorder occurring in 1 in 10,000-16,000 live-born infants. In the general population, approximately 60 people in every 1,000,000 are affected. The condition is characterized by short stature, low lean body mass, muscular hypotonia, mental retardation, behavioral abnormalities, dysmorphic features, and excessive appetite with progressive obesity. Furthermore, morbidity and mortality are high, probably as a result of gross obesity. Most patients have reduced GH secretory capacity and hypogonadotropic hypogonadism, suggesting hypothalamic-pituitary dysfunction. Replacement of GH and/or sex hormones may therefore be beneficial in Prader-Willi syndrome, and several clinical trials have now evaluated GH replacement therapy in affected children. Results of GH treatment have been encouraging: improved growth, increased lean body mass, and reduced fat mass. There was also some evidence of improvements in respiratory function and physical activity. The long-term benefits of GH treatment are, however, still to be established. Similarly, the role of sex hormone replacement therapy needs to be clarified as few data exist on its efficacy and potential benefits. In summary, Prader-Willi syndrome is a disabling condition associated with GH deficiency and hypogonadism. More active treatment of these endocrine disorders is likely to benefit affected individuals." @default.
• W1977047462 created "2016-06-24" @default.
• W1977047462 creator A5018402524 @default.
• W1977047462 creator A5020468514 @default.
• W1977047462 creator A5022847398 @default.
• W1977047462 date "2001-12-01" @default.
• W1977047462 modified "2023-10-02" @default.
• W1977047462 title "Endocrine Dysfunction in Prader-Willi Syndrome: A Review with Special Reference to GH" @default.
• W1977047462 cites W1859829916 @default.
• W1977047462 cites W1964435238 @default.
• W1977047462 cites W1969719527 @default.
• W1977047462 cites W1973861950 @default.
• W1977047462 cites W1974219784 @default.
• W1977047462 cites W1974980610 @default.
• W1977047462 cites W1978876846 @default.
• W1977047462 cites W1979388201 @default.
• W1977047462 cites W1982836278 @default.
• W1977047462 cites W1983598000 @default.
• W1977047462 cites W1984360600 @default.
• W1977047462 cites W1988682537 @default.
• W1977047462 cites W1989700391 @default.
• W1977047462 cites W1991119858 @default.
• W1977047462 cites W1994403043 @default.
• W1977047462 cites W1999766097 @default.
• W1977047462 cites W2001262684 @default.
• W1977047462 cites W2003555013 @default.
• W1977047462 cites W2005431412 @default.
• W1977047462 cites W2006115784 @default.
• W1977047462 cites W2006642580 @default.
• W1977047462 cites W2012094970 @default.
• W1977047462 cites W2016928134 @default.
• W1977047462 cites W2023096075 @default.
• W1977047462 cites W2031538715 @default.
• W1977047462 cites W2033001741 @default.
• W1977047462 cites W2035650082 @default.
• W1977047462 cites W2038391729 @default.
• W1977047462 cites W2040209208 @default.
• W1977047462 cites W2040410296 @default.
• W1977047462 cites W2043005928 @default.
• W1977047462 cites W2045857484 @default.
• W1977047462 cites W2046813663 @default.
• W1977047462 cites W2050784547 @default.
• W1977047462 cites W2051572098 @default.
• W1977047462 cites W2051719562 @default.
• W1977047462 cites W2053285437 @default.
• W1977047462 cites W2053595678 @default.
• W1977047462 cites W2055322868 @default.
• W1977047462 cites W2057625382 @default.
• W1977047462 cites W2057714729 @default.
• W1977047462 cites W2058357563 @default.
• W1977047462 cites W2058602065 @default.
• W1977047462 cites W2061915019 @default.
• W1977047462 cites W2064577176 @default.
• W1977047462 cites W2069083573 @default.
• W1977047462 cites W2072483375 @default.
• W1977047462 cites W2073544325 @default.
• W1977047462 cites W2073569512 @default.
• W1977047462 cites W2075328003 @default.
• W1977047462 cites W2077561525 @default.
• W1977047462 cites W2079350631 @default.
• W1977047462 cites W2079421093 @default.
• W1977047462 cites W2080711201 @default.
• W1977047462 cites W2091977393 @default.
• W1977047462 cites W2092844232 @default.
• W1977047462 cites W2093084887 @default.
• W1977047462 cites W2099396925 @default.
• W1977047462 cites W2103091585 @default.
• W1977047462 cites W2111081143 @default.
• W1977047462 cites W2114845326 @default.
• W1977047462 cites W2115107426 @default.
• W1977047462 cites W2115881045 @default.
• W1977047462 cites W2119310050 @default.
• W1977047462 cites W2122118417 @default.
• W1977047462 cites W2139221740 @default.
• W1977047462 cites W2142286163 @default.
• W1977047462 cites W2144206418 @default.
• W1977047462 cites W2145628226 @default.
• W1977047462 cites W2147449908 @default.
• W1977047462 cites W2149070866 @default.
• W1977047462 cites W2151788908 @default.
• W1977047462 cites W2154502814 @default.
• W1977047462 cites W2157525353 @default.
• W1977047462 cites W2167289583 @default.
• W1977047462 cites W2169243271 @default.
• W1977047462 cites W2171087727 @default.
• W1977047462 cites W2187038841 @default.
• W1977047462 cites W2244492297 @default.
• W1977047462 cites W2318956312 @default.
• W1977047462 cites W2808980419 @default.
• W1977047462 cites W4231874485 @default.
• W1977047462 cites W4322703196 @default.
• W1977047462 cites W69068691 @default.
• W1977047462 doi "https://doi.org/10.1210/edrv.22.6.0447" @default.
• W1977047462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11739333" @default.
• W1977047462 hasPublicationYear "2001" @default.
• W1977047462 type Work @default.
• W1977047462 sameAs 1977047462 @default.
• W1977047462 citedByCount "288" @default.

• next