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- W1977057746 abstract "In glass capillary tubes of less than 0.4 mm radius, the viscosity of erythrocyte suspensions is directly dependent on the tube radius of the viscometer. This is the well known Fahraeus-Lindqvist phenomenon. An equation which describes this relation for dog erythrocyte suspensions is used to compare the pressure required to maintain a resting cardiac output in a dog's circulatory system when it is perfused with blood with the pressure which would be required when the same system is perfused with a hemoglobin solution of comparable oxygen-carrying capacity. Although blood viscosity, as measured in a large bore glass capillary tube, is 42% greater than that of a comparable hemoglobin solution, the pressure required to maintain the flow of blood, 103 mm Hg, is 73% of that necessary to pump the hemoglobin solution, 142 mm Hg. The difference is attributable to the fact that the resistance vessels in the circulatory system have radii below the critical level for the Fåhraeus-Lindqvist phenomenon to occur. These results favor the argument that, in the intact circulatory system, packaging hemoglobin in blood corpuscles would lessen the workload required to maintain a given cardiac output." @default.
- W1977057746 created "2016-06-24" @default.
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- W1977057746 date "1973-12-01" @default.
- W1977057746 modified "2023-10-15" @default.
- W1977057746 title "Erythrocyte evolution: The significance of the Fåhraeus-Lindqvist phenomenon" @default.
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- W1977057746 doi "https://doi.org/10.1016/0034-5687(73)90031-5" @default.
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