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- W1977067701 abstract "Activated T cells in the peripheral blood of patients with systemic lupus erythematosus (SLE) were determined using monoclonal antibodies against activation antigens. Elevated percentages of HLA-DR+ T cells were found in association with active disease. In contrast, we observed an increase in IL-2, receptor-bearing T cells in only six out of 16 patients with active disease. In vitro assays, like spontaneous proliferation, response to IL-2, production of IL-2, and immunoglobulin synthesis have shown that the different patterns of activation antigens are related to different functional stages of T-cell activation. The possible therapeutic consequences are discussed." @default.
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- W1977067701 date "1986-07-01" @default.
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- W1977067701 title "Correlation between the Phenotype and the Functional Capacity of Activated T Cells in Patients with Active Systemic Lupus Erythematosus" @default.
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- W1977067701 doi "https://doi.org/10.1111/j.1365-3083.1986.tb02074.x" @default.
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