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• W1977083313 abstract "Here we describe a knock-in mouse model for Cre-loxP-based conditional expression of TRPV1 in central nervous system neurons. Expression of Cre recombinase using biolistics, lentivirus or genetic intercrosses triggered heterologous expression of TRPV1 in a cell-specific manner. Application of the TRPV1 ligand capsaicin induced strong inward currents, triggered action potentials and activated stereotyped behaviors, allowing cell type-specific chemical genetic control of neuronal activity in vitro and in vivo." @default.
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• W1977083313 date "2008-03-09" @default.
• W1977083313 modified "2023-10-01" @default.
• W1977083313 title "Genetic control of neuronal activity in mice conditionally expressing TRPV1" @default.
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• W1977083313 doi "https://doi.org/10.1038/nmeth.1190" @default.
• W1977083313 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3127246" @default.
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