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- W1977093143 abstract "LAST YEAR (1) we reported the isolation of a protein, ‘metakentrin’ (2), from the hog pituitary gland, which repairs, maintains, and stimulates the interstitial d cells of the testes and ovaries and causes the formation of corpora lutea from preformed graafian follicles. This protein was shown to be homogeneous by ultracentrifugation and electrophoretic analysis and also to possess a constant solubility in one solvent. The view that the protein is the hormone could not be taken as proved. For the sake of simplicity, however, this protein has been referred to as a ‘hormone’ without any qualifications because there are no experimental results known to be in conflict with this view. In this paper we shall describe a simplified procedure for the preparation of the hormone together with experiments consistently supporting the belief that the protein is the hormone rather than an inactive protein on which an extremely active hormone is adsorbed." @default.
- W1977093143 created "2016-06-24" @default.
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- W1977093143 date "1942-05-01" @default.
- W1977093143 modified "2023-09-24" @default.
- W1977093143 title "GONADOTROPINS OF THE SWINE PITUITARY II. PREPARATION, AND BIOLOGICAL AND PHYSICO-CHEMICAL CHARACTERIZATION OF A PROTEIN APPARENTLY IDENTICAL WITH METAKENTRIN (ICSH)" @default.
- W1977093143 doi "https://doi.org/10.1210/endo-30-5-650" @default.
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