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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977121432> ?p ?o ?g. }

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• W1977121432 abstract "A direct HPLC enantioseparation of three representative compounds of a new family of potential non-peptide β-secretase inhibitors was performed on the immobilized Chiralpak IA chiral stationary phase. Semipreparative amounts of enantiopure forms were collected and submitted to stereochemical characterization. The absolute configuration was assigned by a multi-step methodology based on the combination of Mosher's method with circular dichroism (CD) spectroscopy. The results from the NMR/CD study fully correlated the configurational assignment obtained by a second approach involving single crystal X-ray diffraction." @default.
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• W1977121432 date "2010-09-15" @default.
• W1977121432 modified "2023-09-28" @default.
• W1977121432 title "Enantioselective HPLC combined with spectroscopic methods: A valid strategy to determine the absolute configuration of potential β-secretase inhibitors" @default.
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• W1977121432 doi "https://doi.org/10.1016/j.talanta.2010.06.060" @default.
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