Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977136952> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W1977136952 endingPage "1253" @default.
- W1977136952 startingPage "1251" @default.
- W1977136952 abstract "The availability of calcium antagonists has provided yet another therapeutic option in the management of hypertension. Calcium antagonists lower the blood pressure in hypertensive individuals while preserving the blood flow at the microcirculatory level. While all the available calcium antagonists are effective in the treatment of hypertension, they differ in their hemodynamic and pharmacologic actions. Nifedipine appears to be suitable for immediate treatment of severe hypertension and for chronic treatment of uncomplicated or refractory hypertension. In some but not all patients, co-administration of a beta-blocker is necessary to blunt reflex tachycardia. This problem is less likely with the tablet/long-acting formulation of nifedipine. Verapamil and diltiazem are useful as initial therapy for chronic mild-to-moderate hypertension. They are as effective as other first-line drugs in the treatment of uncomplicated hypertension. The heart rate with verapamil or diltiazem does not change or is slightly reduced, thus contrasting with nifedipine. Experience to date suggests that calcium antagonists do not cause adverse biochemical effects and in this respect are superior to diuretics and certain beta-blockers. Currently, verapamil is available as a sustained release preparation. In the near future, nifedipine or diltiazem may also be available in the long acting formulation to permit simplicity and to enhance patient compliance in the treatment of hypertension." @default.
- W1977136952 created "2016-06-24" @default.
- W1977136952 creator A5024442013 @default.
- W1977136952 creator A5052573469 @default.
- W1977136952 date "1988-06-01" @default.
- W1977136952 modified "2023-09-25" @default.
- W1977136952 title "Calcium Antagonists in the Treatment of Hypertension" @default.
- W1977136952 doi "https://doi.org/10.1378/chest.93.6.1251" @default.
- W1977136952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3286142" @default.
- W1977136952 hasPublicationYear "1988" @default.
- W1977136952 type Work @default.
- W1977136952 sameAs 1977136952 @default.
- W1977136952 citedByCount "9" @default.
- W1977136952 countsByYear W19771369522014 @default.
- W1977136952 crossrefType "journal-article" @default.
- W1977136952 hasAuthorship W1977136952A5024442013 @default.
- W1977136952 hasAuthorship W1977136952A5052573469 @default.
- W1977136952 hasConcept C126322002 @default.
- W1977136952 hasConcept C164705383 @default.
- W1977136952 hasConcept C2776741139 @default.
- W1977136952 hasConcept C2777022698 @default.
- W1977136952 hasConcept C2778043224 @default.
- W1977136952 hasConcept C2779066535 @default.
- W1977136952 hasConcept C2780283014 @default.
- W1977136952 hasConcept C42219234 @default.
- W1977136952 hasConcept C519063684 @default.
- W1977136952 hasConcept C71924100 @default.
- W1977136952 hasConcept C84393581 @default.
- W1977136952 hasConcept C98274493 @default.
- W1977136952 hasConceptScore W1977136952C126322002 @default.
- W1977136952 hasConceptScore W1977136952C164705383 @default.
- W1977136952 hasConceptScore W1977136952C2776741139 @default.
- W1977136952 hasConceptScore W1977136952C2777022698 @default.
- W1977136952 hasConceptScore W1977136952C2778043224 @default.
- W1977136952 hasConceptScore W1977136952C2779066535 @default.
- W1977136952 hasConceptScore W1977136952C2780283014 @default.
- W1977136952 hasConceptScore W1977136952C42219234 @default.
- W1977136952 hasConceptScore W1977136952C519063684 @default.
- W1977136952 hasConceptScore W1977136952C71924100 @default.
- W1977136952 hasConceptScore W1977136952C84393581 @default.
- W1977136952 hasConceptScore W1977136952C98274493 @default.
- W1977136952 hasIssue "6" @default.
- W1977136952 hasLocation W19771369521 @default.
- W1977136952 hasLocation W19771369522 @default.
- W1977136952 hasOpenAccess W1977136952 @default.
- W1977136952 hasPrimaryLocation W19771369521 @default.
- W1977136952 hasRelatedWork W1965546722 @default.
- W1977136952 hasRelatedWork W1972225279 @default.
- W1977136952 hasRelatedWork W2034698869 @default.
- W1977136952 hasRelatedWork W2047015874 @default.
- W1977136952 hasRelatedWork W2090134883 @default.
- W1977136952 hasRelatedWork W2148282970 @default.
- W1977136952 hasRelatedWork W2342174312 @default.
- W1977136952 hasRelatedWork W4231450703 @default.
- W1977136952 hasRelatedWork W63024063 @default.
- W1977136952 hasRelatedWork W2001641233 @default.
- W1977136952 hasVolume "93" @default.
- W1977136952 isParatext "false" @default.
- W1977136952 isRetracted "false" @default.
- W1977136952 magId "1977136952" @default.
- W1977136952 workType "article" @default.