Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977166521> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1977166521 endingPage "170" @default.
- W1977166521 startingPage "165" @default.
- W1977166521 abstract "Adult-type hypolactasia (AtH) can be diagnosed by genotyping in addition to functional tests or intestinal biopsy. The aims of this study were to estimate the prevalence of AtH by genotyping and to investigate whether AtH prevalence has changed in Sweden during the 20th century.Schoolchildren (n=690) born in 1983 and 1989, and elderly individuals (n=392) born between 1920 and 1932 were genotyped for AtH using Pyrosequencing technology.The overall prevalence of AtH among children was 14.1%. The majority of children (92%, n=635) were Caucasians with genotype prevalences: CC, 61 (10%); CT, 259 (41%); TT, 307 (49%). The frequency of the mutated allele q was 0.300 in this cohort. The prevalence of AtH estimated from the Hardy-Weinberg equilibrium (HWE) (q 2), was 9.0% (95% CI: 6.7-11.2%). Eight percent (n=55) of the children were non-Caucasian; genotype prevalences were CC, 36 (66%); CT, 15 (27%); TT, 4 (7%). The prevalence of AtH in these children estimated from HWE was 62.5% (95% CI: 49.7-75.3%). The elderly subjects were all Caucasians. Their genotype prevalences were: CC, 20 (5%); CT, 166 (42%); TT, 206 (53%); the frequency of the mutated allele q was 0.262 and their AtH prevalence estimated from HWE was 6.8% (95% CI: 4.3-9.2%).The overall prevalence of AtH in children (14%) was higher than previously thought. Among Caucasians, higher figures were seen in children than in the elderly (9% versus 6.8%). The prevalence thus seems to be increasing and this may be due to the immigration of both non-Caucasian and Caucasian groups with a higher prevalence of AtH." @default.
- W1977166521 created "2016-06-24" @default.
- W1977166521 creator A5002006510 @default.
- W1977166521 creator A5021804500 @default.
- W1977166521 creator A5022751655 @default.
- W1977166521 creator A5028374184 @default.
- W1977166521 creator A5029358528 @default.
- W1977166521 date "2007-01-01" @default.
- W1977166521 modified "2023-10-17" @default.
- W1977166521 title "Prevalence and trends in adult-type hypolactasia in different age cohorts in Central Sweden diagnosed by genotyping for the adult-type hypolactasia-linked LCT –13910C > T mutation" @default.
- W1977166521 cites W1967672777 @default.
- W1977166521 cites W1974976554 @default.
- W1977166521 cites W1985448630 @default.
- W1977166521 cites W1991739137 @default.
- W1977166521 cites W2001722477 @default.
- W1977166521 cites W2003489630 @default.
- W1977166521 cites W2009171533 @default.
- W1977166521 cites W2011389138 @default.
- W1977166521 cites W2012345358 @default.
- W1977166521 cites W2021992593 @default.
- W1977166521 cites W2051054384 @default.
- W1977166521 cites W2067991539 @default.
- W1977166521 cites W2085422457 @default.
- W1977166521 cites W2091069645 @default.
- W1977166521 cites W2096758237 @default.
- W1977166521 cites W2102482027 @default.
- W1977166521 cites W2105075170 @default.
- W1977166521 cites W2112839594 @default.
- W1977166521 cites W2124692188 @default.
- W1977166521 cites W2156393575 @default.
- W1977166521 cites W4299541906 @default.
- W1977166521 doi "https://doi.org/10.1080/00365520600825257" @default.
- W1977166521 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17327935" @default.
- W1977166521 hasPublicationYear "2007" @default.
- W1977166521 type Work @default.
- W1977166521 sameAs 1977166521 @default.
- W1977166521 citedByCount "34" @default.
- W1977166521 countsByYear W19771665212012 @default.
- W1977166521 countsByYear W19771665212013 @default.
- W1977166521 countsByYear W19771665212014 @default.
- W1977166521 countsByYear W19771665212015 @default.
- W1977166521 countsByYear W19771665212016 @default.
- W1977166521 countsByYear W19771665212018 @default.
- W1977166521 countsByYear W19771665212019 @default.
- W1977166521 countsByYear W19771665212020 @default.
- W1977166521 countsByYear W19771665212021 @default.
- W1977166521 crossrefType "journal-article" @default.
- W1977166521 hasAuthorship W1977166521A5002006510 @default.
- W1977166521 hasAuthorship W1977166521A5021804500 @default.
- W1977166521 hasAuthorship W1977166521A5022751655 @default.
- W1977166521 hasAuthorship W1977166521A5028374184 @default.
- W1977166521 hasAuthorship W1977166521A5029358528 @default.
- W1977166521 hasConcept C104317684 @default.
- W1977166521 hasConcept C126322002 @default.
- W1977166521 hasConcept C135763542 @default.
- W1977166521 hasConcept C144024400 @default.
- W1977166521 hasConcept C149923435 @default.
- W1977166521 hasConcept C187212893 @default.
- W1977166521 hasConcept C31467283 @default.
- W1977166521 hasConcept C37463918 @default.
- W1977166521 hasConcept C54355233 @default.
- W1977166521 hasConcept C71924100 @default.
- W1977166521 hasConcept C72563966 @default.
- W1977166521 hasConcept C86803240 @default.
- W1977166521 hasConcept C90924648 @default.
- W1977166521 hasConceptScore W1977166521C104317684 @default.
- W1977166521 hasConceptScore W1977166521C126322002 @default.
- W1977166521 hasConceptScore W1977166521C135763542 @default.
- W1977166521 hasConceptScore W1977166521C144024400 @default.
- W1977166521 hasConceptScore W1977166521C149923435 @default.
- W1977166521 hasConceptScore W1977166521C187212893 @default.
- W1977166521 hasConceptScore W1977166521C31467283 @default.
- W1977166521 hasConceptScore W1977166521C37463918 @default.
- W1977166521 hasConceptScore W1977166521C54355233 @default.
- W1977166521 hasConceptScore W1977166521C71924100 @default.
- W1977166521 hasConceptScore W1977166521C72563966 @default.
- W1977166521 hasConceptScore W1977166521C86803240 @default.
- W1977166521 hasConceptScore W1977166521C90924648 @default.
- W1977166521 hasIssue "2" @default.
- W1977166521 hasLocation W19771665211 @default.
- W1977166521 hasLocation W19771665212 @default.
- W1977166521 hasOpenAccess W1977166521 @default.
- W1977166521 hasPrimaryLocation W19771665211 @default.
- W1977166521 hasRelatedWork W1506810331 @default.
- W1977166521 hasRelatedWork W1974800692 @default.
- W1977166521 hasRelatedWork W2051135531 @default.
- W1977166521 hasRelatedWork W2386772098 @default.
- W1977166521 hasRelatedWork W2768580332 @default.
- W1977166521 hasRelatedWork W2810362112 @default.
- W1977166521 hasRelatedWork W2972558724 @default.
- W1977166521 hasRelatedWork W2979618531 @default.
- W1977166521 hasRelatedWork W3203513527 @default.
- W1977166521 hasRelatedWork W2461510400 @default.
- W1977166521 hasVolume "42" @default.
- W1977166521 isParatext "false" @default.
- W1977166521 isRetracted "false" @default.
- W1977166521 magId "1977166521" @default.
- W1977166521 workType "article" @default.