Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977180512> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W1977180512 endingPage "64" @default.
- W1977180512 startingPage "57" @default.
- W1977180512 abstract "Information regarding the biology and virulence attributes of Treponema pallidum (Tp) is limited due to the lack of genetic exchange mechanisms and the inability to continuously cultivate this spirochete. We have utilized TnphoA mutagenesis of a Tp genomic DNA library in Escherichia coli (Ec) to identify genes encoding exported proteins, a subset of which are likely to be important in treponemal pathogenesis. We report here the identification and nucleotide (nt) sequence of a 5-kb treponemal DNA insert that contains seven open reading frames (ORFs). The proteins encoded by six of these ORFs have homology with members of a newly described protein family involved in the biogenesis/assembly of flagella and the control of flagellar rotation in Ec, Salmonella typhimurium (St) and Bacillus subtilis (Bs). Certain members of this family are also involved in the export of virulence factors in Yersinia (Yr) spp., St and Shigella flexneri (Sf). We have named these six ORFs fliM', fliY, fliP, fliQ, fliR and flhB'. The operon containing these ORFs has been designated as the fla operon. We hypothesize that the protein products of these genes are involved in the biogenesis/assembly of flagella and the control of flagellar rotation in Tp." @default.
- W1977180512 created "2016-06-24" @default.
- W1977180512 creator A5002630168 @default.
- W1977180512 creator A5064209833 @default.
- W1977180512 creator A5089942700 @default.
- W1977180512 date "1995-12-01" @default.
- W1977180512 modified "2023-09-27" @default.
- W1977180512 title "Identification and sequences of the Treponema pallidum fliM', fli Y, fliP, fliQ, fliR and flhB' genes" @default.
- W1977180512 cites W1481948789 @default.
- W1977180512 cites W1510366674 @default.
- W1977180512 cites W1596140174 @default.
- W1977180512 cites W1599017802 @default.
- W1977180512 cites W1647750839 @default.
- W1977180512 cites W1710835694 @default.
- W1977180512 cites W1817282511 @default.
- W1977180512 cites W1828452608 @default.
- W1977180512 cites W1910369247 @default.
- W1977180512 cites W1916816096 @default.
- W1977180512 cites W1918008828 @default.
- W1977180512 cites W1929958215 @default.
- W1977180512 cites W1932755342 @default.
- W1977180512 cites W1941008597 @default.
- W1977180512 cites W1966792663 @default.
- W1977180512 cites W1971424582 @default.
- W1977180512 cites W1997479358 @default.
- W1977180512 cites W2000207368 @default.
- W1977180512 cites W2025499755 @default.
- W1977180512 cites W2032606946 @default.
- W1977180512 cites W2084205512 @default.
- W1977180512 cites W2114879192 @default.
- W1977180512 cites W2135145200 @default.
- W1977180512 cites W2154000715 @default.
- W1977180512 cites W2157851607 @default.
- W1977180512 cites W2172608051 @default.
- W1977180512 doi "https://doi.org/10.1016/0378-1119(95)00583-x" @default.
- W1977180512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8529894" @default.
- W1977180512 hasPublicationYear "1995" @default.
- W1977180512 type Work @default.
- W1977180512 sameAs 1977180512 @default.
- W1977180512 citedByCount "21" @default.
- W1977180512 countsByYear W19771805122013 @default.
- W1977180512 countsByYear W19771805122014 @default.
- W1977180512 crossrefType "journal-article" @default.
- W1977180512 hasAuthorship W1977180512A5002630168 @default.
- W1977180512 hasAuthorship W1977180512A5064209833 @default.
- W1977180512 hasAuthorship W1977180512A5089942700 @default.
- W1977180512 hasConcept C104317684 @default.
- W1977180512 hasConcept C115811362 @default.
- W1977180512 hasConcept C159047783 @default.
- W1977180512 hasConcept C167625842 @default.
- W1977180512 hasConcept C203075996 @default.
- W1977180512 hasConcept C2776983459 @default.
- W1977180512 hasConcept C2780187896 @default.
- W1977180512 hasConcept C2780530800 @default.
- W1977180512 hasConcept C2781217973 @default.
- W1977180512 hasConcept C3013748606 @default.
- W1977180512 hasConcept C47289529 @default.
- W1977180512 hasConcept C54355233 @default.
- W1977180512 hasConcept C547475151 @default.
- W1977180512 hasConcept C60987743 @default.
- W1977180512 hasConcept C86803240 @default.
- W1977180512 hasConceptScore W1977180512C104317684 @default.
- W1977180512 hasConceptScore W1977180512C115811362 @default.
- W1977180512 hasConceptScore W1977180512C159047783 @default.
- W1977180512 hasConceptScore W1977180512C167625842 @default.
- W1977180512 hasConceptScore W1977180512C203075996 @default.
- W1977180512 hasConceptScore W1977180512C2776983459 @default.
- W1977180512 hasConceptScore W1977180512C2780187896 @default.
- W1977180512 hasConceptScore W1977180512C2780530800 @default.
- W1977180512 hasConceptScore W1977180512C2781217973 @default.
- W1977180512 hasConceptScore W1977180512C3013748606 @default.
- W1977180512 hasConceptScore W1977180512C47289529 @default.
- W1977180512 hasConceptScore W1977180512C54355233 @default.
- W1977180512 hasConceptScore W1977180512C547475151 @default.
- W1977180512 hasConceptScore W1977180512C60987743 @default.
- W1977180512 hasConceptScore W1977180512C86803240 @default.
- W1977180512 hasIssue "1" @default.
- W1977180512 hasLocation W19771805121 @default.
- W1977180512 hasLocation W19771805122 @default.
- W1977180512 hasOpenAccess W1977180512 @default.
- W1977180512 hasPrimaryLocation W19771805121 @default.
- W1977180512 hasRelatedWork W1948731625 @default.
- W1977180512 hasRelatedWork W1977180512 @default.
- W1977180512 hasRelatedWork W1987905608 @default.
- W1977180512 hasRelatedWork W2025707179 @default.
- W1977180512 hasRelatedWork W2027674732 @default.
- W1977180512 hasRelatedWork W2074599985 @default.
- W1977180512 hasRelatedWork W2091975280 @default.
- W1977180512 hasRelatedWork W2117063418 @default.
- W1977180512 hasRelatedWork W2167112782 @default.
- W1977180512 hasRelatedWork W2498907773 @default.
- W1977180512 hasVolume "166" @default.
- W1977180512 isParatext "false" @default.
- W1977180512 isRetracted "false" @default.
- W1977180512 magId "1977180512" @default.
- W1977180512 workType "article" @default.