Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977189931> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1977189931 endingPage "1174" @default.
- W1977189931 startingPage "1171" @default.
- W1977189931 abstract "Previous work indicated that high mobility group box-1 (HMGB1) protein may be involved in neutrophilic asthma. Here, we sought to investigate the correlation between HMGB1 and one of its receptors, receptor for advanced glycosylation end products (RAGE), with the severity of bronchial asthma. Compared to the control group (30 healthy individuals), patients in the asthma group (n=72) exhibited a higher percentage of neutrophils and higher HMGB1 and RAGE levels in induced sputum samples (P<0.05). Concurrently, FEV(1)% was significantly lower in the asthma group (P<0.05). Further, compared to mild and moderate asthma, in patients with severe asthma ACQ scores, the percentage of neutrophils, and HMGB1 levels were significantly higher, while FEV(1)% was significantly lower (P<0.05). The percentage of neutrophils and HMGB1 and RAGE levels were lower after treatment than before treatment (P<0.05). Finally, negative correlations were observed between HMGB1 or RAGE levels and FEV(1)% (r=-0.777 and r=-0.291, P<0.05), and positive correlations were detected between HMGB1 or RAGE levels and percentage of neutrophils (r=0.803 and r=0.326, P<0.05). Additionally, positive correlations were observed between HMGB1 and RAGE levels within the asthma group (r=0.306, P<0.05). Therefore, HMGB1 protein levels correlate with the severity of asthma, and HMGB1 may contribute to the inflammatory process of asthma." @default.
- W1977189931 created "2016-06-24" @default.
- W1977189931 creator A5006487429 @default.
- W1977189931 creator A5016510715 @default.
- W1977189931 creator A5034159290 @default.
- W1977189931 creator A5044126585 @default.
- W1977189931 creator A5049352241 @default.
- W1977189931 creator A5058119909 @default.
- W1977189931 creator A5090484658 @default.
- W1977189931 date "2012-11-01" @default.
- W1977189931 modified "2023-10-03" @default.
- W1977189931 title "HMGB1 and RAGE levels in induced sputum correlate with asthma severity and neutrophil percentage" @default.
- W1977189931 cites W1976552088 @default.
- W1977189931 cites W1995177733 @default.
- W1977189931 cites W2083419397 @default.
- W1977189931 cites W2095609344 @default.
- W1977189931 cites W2097847091 @default.
- W1977189931 cites W2097862839 @default.
- W1977189931 cites W2125175295 @default.
- W1977189931 cites W2130775443 @default.
- W1977189931 cites W2137874745 @default.
- W1977189931 cites W2153801667 @default.
- W1977189931 cites W2159638894 @default.
- W1977189931 cites W2164714222 @default.
- W1977189931 cites W2171028311 @default.
- W1977189931 doi "https://doi.org/10.1016/j.humimm.2012.08.016" @default.
- W1977189931 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22960399" @default.
- W1977189931 hasPublicationYear "2012" @default.
- W1977189931 type Work @default.
- W1977189931 sameAs 1977189931 @default.
- W1977189931 citedByCount "43" @default.
- W1977189931 countsByYear W19771899312013 @default.
- W1977189931 countsByYear W19771899312014 @default.
- W1977189931 countsByYear W19771899312015 @default.
- W1977189931 countsByYear W19771899312016 @default.
- W1977189931 countsByYear W19771899312017 @default.
- W1977189931 countsByYear W19771899312018 @default.
- W1977189931 countsByYear W19771899312019 @default.
- W1977189931 countsByYear W19771899312020 @default.
- W1977189931 countsByYear W19771899312021 @default.
- W1977189931 countsByYear W19771899312022 @default.
- W1977189931 countsByYear W19771899312023 @default.
- W1977189931 crossrefType "journal-article" @default.
- W1977189931 hasAuthorship W1977189931A5006487429 @default.
- W1977189931 hasAuthorship W1977189931A5016510715 @default.
- W1977189931 hasAuthorship W1977189931A5034159290 @default.
- W1977189931 hasAuthorship W1977189931A5044126585 @default.
- W1977189931 hasAuthorship W1977189931A5049352241 @default.
- W1977189931 hasAuthorship W1977189931A5058119909 @default.
- W1977189931 hasAuthorship W1977189931A5090484658 @default.
- W1977189931 hasConcept C126322002 @default.
- W1977189931 hasConcept C142724271 @default.
- W1977189931 hasConcept C169760540 @default.
- W1977189931 hasConcept C170493617 @default.
- W1977189931 hasConcept C203014093 @default.
- W1977189931 hasConcept C2776042228 @default.
- W1977189931 hasConcept C2776301714 @default.
- W1977189931 hasConcept C2778857457 @default.
- W1977189931 hasConcept C2780545709 @default.
- W1977189931 hasConcept C2781069245 @default.
- W1977189931 hasConcept C71924100 @default.
- W1977189931 hasConcept C86803240 @default.
- W1977189931 hasConceptScore W1977189931C126322002 @default.
- W1977189931 hasConceptScore W1977189931C142724271 @default.
- W1977189931 hasConceptScore W1977189931C169760540 @default.
- W1977189931 hasConceptScore W1977189931C170493617 @default.
- W1977189931 hasConceptScore W1977189931C203014093 @default.
- W1977189931 hasConceptScore W1977189931C2776042228 @default.
- W1977189931 hasConceptScore W1977189931C2776301714 @default.
- W1977189931 hasConceptScore W1977189931C2778857457 @default.
- W1977189931 hasConceptScore W1977189931C2780545709 @default.
- W1977189931 hasConceptScore W1977189931C2781069245 @default.
- W1977189931 hasConceptScore W1977189931C71924100 @default.
- W1977189931 hasConceptScore W1977189931C86803240 @default.
- W1977189931 hasIssue "11" @default.
- W1977189931 hasLocation W19771899311 @default.
- W1977189931 hasLocation W19771899312 @default.
- W1977189931 hasOpenAccess W1977189931 @default.
- W1977189931 hasPrimaryLocation W19771899311 @default.
- W1977189931 hasRelatedWork W1507020767 @default.
- W1977189931 hasRelatedWork W1995801352 @default.
- W1977189931 hasRelatedWork W2027819189 @default.
- W1977189931 hasRelatedWork W2078213156 @default.
- W1977189931 hasRelatedWork W2109334664 @default.
- W1977189931 hasRelatedWork W2154956771 @default.
- W1977189931 hasRelatedWork W2389335086 @default.
- W1977189931 hasRelatedWork W2520660888 @default.
- W1977189931 hasRelatedWork W2953281046 @default.
- W1977189931 hasRelatedWork W2185536236 @default.
- W1977189931 hasVolume "73" @default.
- W1977189931 isParatext "false" @default.
- W1977189931 isRetracted "false" @default.
- W1977189931 magId "1977189931" @default.
- W1977189931 workType "article" @default.