Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977201475> ?p ?o ?g. }
- W1977201475 endingPage "1060" @default.
- W1977201475 startingPage "1051" @default.
- W1977201475 abstract "Wistar rats (body wt. 200 g) were subjected to a fractionated course of radiation similar to that used in prophylactic brain irradiation for small cell carcinoma of the lung (2000 cGy in 5 fractions over 5 days with 60Co). Effects of this regimen were assessed by histologic examination of brain sections at 1 week, 1 month and 6 months post-irradiation. With conventional stains there were no apparent differences between control and irradiated brains at any of the post-irradiation intervals. Immunohistochemistry for neurotransmitter synthetic enzymes tyrosine hydroxylase and glutamate decarboxylase, as well as histochemistry for acetylcholinesterase, failed to uncover any changes in the irradiated animals. Immunohistochemistry for glial fibrillary acidic protein, an astrocyte marker, also showed no differences in the irradiated groups. However, an antibody against a major histocompatibility complex, class II antigen (OX-6) revealed a microglial response in grey and white matter beginning at 1 month and increasing up to the 6 month post-irradiation interval. The neuroanatomical basis for this microglial response was suggested by the results of silver stains for nerve axons, which revealed axonal loss in striatal white matter bundles in a pattern implicating vascular insufficiency." @default.
- W1977201475 created "2016-06-24" @default.
- W1977201475 creator A5006757662 @default.
- W1977201475 creator A5072613176 @default.
- W1977201475 creator A5072830866 @default.
- W1977201475 creator A5075024697 @default.
- W1977201475 date "1990-05-01" @default.
- W1977201475 modified "2023-10-03" @default.
- W1977201475 title "An animal model of prophylactic cranial irradiation: Histologic effects at acute, early and delayed stages" @default.
- W1977201475 cites W134357321 @default.
- W1977201475 cites W1895175204 @default.
- W1977201475 cites W1963761563 @default.
- W1977201475 cites W1967527816 @default.
- W1977201475 cites W1972498556 @default.
- W1977201475 cites W1974262012 @default.
- W1977201475 cites W1974924674 @default.
- W1977201475 cites W1979746467 @default.
- W1977201475 cites W1979762396 @default.
- W1977201475 cites W1981262000 @default.
- W1977201475 cites W1989449291 @default.
- W1977201475 cites W1990004358 @default.
- W1977201475 cites W1990835112 @default.
- W1977201475 cites W1994459017 @default.
- W1977201475 cites W1994486755 @default.
- W1977201475 cites W1994704767 @default.
- W1977201475 cites W2002275311 @default.
- W1977201475 cites W2014236713 @default.
- W1977201475 cites W2014719627 @default.
- W1977201475 cites W2017816252 @default.
- W1977201475 cites W2019737348 @default.
- W1977201475 cites W2020074406 @default.
- W1977201475 cites W2026899098 @default.
- W1977201475 cites W2031710238 @default.
- W1977201475 cites W2041725073 @default.
- W1977201475 cites W2042729591 @default.
- W1977201475 cites W2044290944 @default.
- W1977201475 cites W2045680971 @default.
- W1977201475 cites W2047886595 @default.
- W1977201475 cites W2052198304 @default.
- W1977201475 cites W2060148890 @default.
- W1977201475 cites W2062223379 @default.
- W1977201475 cites W2068383507 @default.
- W1977201475 cites W2073005838 @default.
- W1977201475 cites W2074274825 @default.
- W1977201475 cites W2078305681 @default.
- W1977201475 cites W2090258462 @default.
- W1977201475 cites W2090733401 @default.
- W1977201475 cites W2091679619 @default.
- W1977201475 cites W2093536022 @default.
- W1977201475 cites W2102250903 @default.
- W1977201475 cites W2102257509 @default.
- W1977201475 cites W2102796334 @default.
- W1977201475 cites W2110740250 @default.
- W1977201475 cites W2127947104 @default.
- W1977201475 cites W2131533245 @default.
- W1977201475 cites W2162091746 @default.
- W1977201475 cites W2167860836 @default.
- W1977201475 cites W2182914054 @default.
- W1977201475 cites W2262546632 @default.
- W1977201475 cites W248630271 @default.
- W1977201475 cites W3152427583 @default.
- W1977201475 doi "https://doi.org/10.1016/0360-3016(90)90440-u" @default.
- W1977201475 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2347714" @default.
- W1977201475 hasPublicationYear "1990" @default.
- W1977201475 type Work @default.
- W1977201475 sameAs 1977201475 @default.
- W1977201475 citedByCount "71" @default.
- W1977201475 countsByYear W19772014752012 @default.
- W1977201475 countsByYear W19772014752013 @default.
- W1977201475 countsByYear W19772014752015 @default.
- W1977201475 countsByYear W19772014752017 @default.
- W1977201475 countsByYear W19772014752018 @default.
- W1977201475 countsByYear W19772014752019 @default.
- W1977201475 countsByYear W19772014752020 @default.
- W1977201475 countsByYear W19772014752021 @default.
- W1977201475 crossrefType "journal-article" @default.
- W1977201475 hasAuthorship W1977201475A5006757662 @default.
- W1977201475 hasAuthorship W1977201475A5072613176 @default.
- W1977201475 hasAuthorship W1977201475A5072830866 @default.
- W1977201475 hasAuthorship W1977201475A5075024697 @default.
- W1977201475 hasConcept C126322002 @default.
- W1977201475 hasConcept C126838900 @default.
- W1977201475 hasConcept C142724271 @default.
- W1977201475 hasConcept C143409427 @default.
- W1977201475 hasConcept C159167319 @default.
- W1977201475 hasConcept C204232928 @default.
- W1977201475 hasConcept C2777542381 @default.
- W1977201475 hasConcept C2780495277 @default.
- W1977201475 hasConcept C2781192897 @default.
- W1977201475 hasConcept C529278444 @default.
- W1977201475 hasConcept C71924100 @default.
- W1977201475 hasConceptScore W1977201475C126322002 @default.
- W1977201475 hasConceptScore W1977201475C126838900 @default.
- W1977201475 hasConceptScore W1977201475C142724271 @default.
- W1977201475 hasConceptScore W1977201475C143409427 @default.
- W1977201475 hasConceptScore W1977201475C159167319 @default.
- W1977201475 hasConceptScore W1977201475C204232928 @default.
- W1977201475 hasConceptScore W1977201475C2777542381 @default.