FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1977216892> ?p ?o ?g. }

• W1977216892 abstract "Apoptosis is a morphologically distinct form of cell death involved in many physiological and pathological processes. Expression of the CD95 (APO-1/Fas) ligand (CD95L) is critically involved in activation-induced cell death (AICD) of activated T cells. Here we show that the natural free radical scavenger vitamin E suppresses the activity of the transcription factors NF-kappa B and AP-1, thus blocking expression of CD95L and preventing T cell AICD. Since AICD is a major cause of T cell depletion in AIDS, we examined 35 HIV-1-positive individuals and found that their T cells are more susceptible to AICD than are T cells isolated from healthy controls. Administration of vitamin E suppresses CD95L mRNA expression and protects T cells of HIV-1-infected individuals from CD95-mediated apoptosis. This evidence that vitamin E can affect T cell survival may merit further clinical investigation." @default.
• W1977216892 created "2016-06-24" @default.
• W1977216892 creator A5000025317 @default.
• W1977216892 creator A5013990738 @default.
• W1977216892 creator A5030410677 @default.
• W1977216892 creator A5040811817 @default.
• W1977216892 creator A5041826568 @default.
• W1977216892 creator A5042207779 @default.
• W1977216892 creator A5046073740 @default.
• W1977216892 creator A5068388891 @default.
• W1977216892 creator A5069373287 @default.
• W1977216892 date "2002-09-01" @default.
• W1977216892 modified "2023-10-17" @default.
• W1977216892 title "Vitamin E inhibits CD95 ligand expression and protects T cells from activation-induced cell death" @default.
• W1977216892 cites W1514013474 @default.
• W1977216892 cites W1514116720 @default.
• W1977216892 cites W1520653192 @default.
• W1977216892 cites W1583483795 @default.
• W1977216892 cites W1602131003 @default.
• W1977216892 cites W1642763135 @default.
• W1977216892 cites W1794979908 @default.
• W1977216892 cites W1964895167 @default.
• W1977216892 cites W1965392140 @default.
• W1977216892 cites W1973381820 @default.
• W1977216892 cites W1974393084 @default.
• W1977216892 cites W1978018492 @default.
• W1977216892 cites W1994224419 @default.
• W1977216892 cites W1996571869 @default.
• W1977216892 cites W1996755610 @default.
• W1977216892 cites W1997177647 @default.
• W1977216892 cites W1998018344 @default.
• W1977216892 cites W2002733542 @default.
• W1977216892 cites W2004457956 @default.
• W1977216892 cites W2004645606 @default.
• W1977216892 cites W2006249265 @default.
• W1977216892 cites W2007253851 @default.
• W1977216892 cites W2011058948 @default.
• W1977216892 cites W2020285421 @default.
• W1977216892 cites W2021152243 @default.
• W1977216892 cites W2021911222 @default.
• W1977216892 cites W2023809975 @default.
• W1977216892 cites W2027991645 @default.
• W1977216892 cites W2032531389 @default.
• W1977216892 cites W2038752308 @default.
• W1977216892 cites W2040172490 @default.
• W1977216892 cites W2040895935 @default.
• W1977216892 cites W2050903066 @default.
• W1977216892 cites W2052486918 @default.
• W1977216892 cites W2073994420 @default.
• W1977216892 cites W2074192294 @default.
• W1977216892 cites W2075809552 @default.
• W1977216892 cites W2080375720 @default.
• W1977216892 cites W2080722863 @default.
• W1977216892 cites W2086313080 @default.
• W1977216892 cites W2096654683 @default.
• W1977216892 cites W2097106158 @default.
• W1977216892 cites W2098470831 @default.
• W1977216892 cites W2117644728 @default.
• W1977216892 cites W2122559077 @default.
• W1977216892 cites W2129971278 @default.
• W1977216892 cites W2134642581 @default.
• W1977216892 cites W2136242443 @default.
• W1977216892 cites W2140743914 @default.
• W1977216892 cites W2164578725 @default.
• W1977216892 cites W2403444701 @default.
• W1977216892 cites W2410250787 @default.
• W1977216892 cites W2414676408 @default.
• W1977216892 cites W302802154 @default.
• W1977216892 cites W39416069 @default.
• W1977216892 cites W82184047 @default.
• W1977216892 cites W89020728 @default.
• W1977216892 cites W89257037 @default.
• W1977216892 doi "https://doi.org/10.1172/jci15073" @default.
• W1977216892 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/151103" @default.
• W1977216892 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12208869" @default.
• W1977216892 hasPublicationYear "2002" @default.
• W1977216892 type Work @default.
• W1977216892 sameAs 1977216892 @default.
• W1977216892 citedByCount "23" @default.
• W1977216892 countsByYear W19772168922015 @default.
• W1977216892 countsByYear W19772168922016 @default.
• W1977216892 countsByYear W19772168922017 @default.
• W1977216892 countsByYear W19772168922018 @default.
• W1977216892 countsByYear W19772168922019 @default.
• W1977216892 countsByYear W19772168922020 @default.
• W1977216892 countsByYear W19772168922021 @default.
• W1977216892 countsByYear W19772168922023 @default.
• W1977216892 crossrefType "journal-article" @default.
• W1977216892 hasAuthorship W1977216892A5000025317 @default.
• W1977216892 hasAuthorship W1977216892A5013990738 @default.
• W1977216892 hasAuthorship W1977216892A5030410677 @default.
• W1977216892 hasAuthorship W1977216892A5040811817 @default.
• W1977216892 hasAuthorship W1977216892A5041826568 @default.
• W1977216892 hasAuthorship W1977216892A5042207779 @default.
• W1977216892 hasAuthorship W1977216892A5046073740 @default.
• W1977216892 hasAuthorship W1977216892A5068388891 @default.
• W1977216892 hasAuthorship W1977216892A5069373287 @default.
• W1977216892 hasBestOaLocation W19772168921 @default.
• W1977216892 hasConcept C1491633281 @default.
• W1977216892 hasConcept C153911025 @default.

• next