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- W1977278052 abstract "The antioxidant and immunomodulatory effect of an α-glucan (designated here as MT-α-glucan) from fruit body of Maitake mushroom (Grifola frondosa) on D-galactose (D-gal)-induced senescent mice model was evaluated. Results showed that MT-α-glucan could ameliorate age-related alternations in both motor and memory activities of senescent mice. Treatment with MT-α-glucan (450 or 150 mg kg−1) significantly increased the body weight, hepatic superoxide dismutase and glutathione peroxidase activity, reduced glutathione content, the proliferative response and interleukine-2 (IL-2) production of splenocytes induced by ConA. Treatment with MT-α-glucan significantly decreased hepatic malondialdehyde content, the levels of macrophage proliferative response and IL-1 and NO production. These data suggest that MT-α-glucan has antioxidative and immunomodulatory effects on D-gal-induced senescent mice." @default.
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- W1977278052 date "2013-12-01" @default.
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- W1977278052 title "Antioxidant and immunomodulatory effects of a α-glucan from fruit body of maitake (<i>Grifola frondosa</i>)" @default.
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- W1977278052 doi "https://doi.org/10.1080/09540105.2012.704901" @default.
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